Dietary restriction delays the secretion of senescence associated secretory phenotype by reducing DNA damage response in the process of renal aging
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2017.09.005
Abstract: ABSTRACT Dietary restriction (DR) has multiple and essential effects in protecting against DNA damage in model organisms. Persistent DNA damage plays a central role in the process of aging. Senescence‐associated secretory phenotype (SASP), as a… read more here.
Keywords: dna damage; senescence; process; dietary restriction ... See more keywords
Rejuvenation: Turning back the clock of aging kidney.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Formosan Medical Association = Taiwan yi zhi"
DOI: 10.1016/j.jfma.2019.05.020
Abstract: Aging is inevitable in life. It is defined as impaired adaptive capacity to environmental or internal stresses with growing rates of disease and death. Aging is also an important risk factor for various kidney diseases… read more here.
Keywords: clock aging; turning back; rejuvenation turning; back clock ... See more keywords
PTEN-induced kinase 1 is associated with renal aging, via the cGAS-STING pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Aging cell"
DOI: 10.1111/acel.13865
Abstract: Mitochondrial dysfunction is considered to be an important mediator of the pro-aging process in chronic kidney disease, which is continuously increasing worldwide. Although PTEN-induced kinase 1 (PINK1) regulates mitochondrial function, its role in renal aging… read more here.
Keywords: sting pathway; senescence; renal aging; cgas sting ... See more keywords