The Hepato-Hypothalamic-Pituitary-Adrenal-Renal Axis: Mathematical Modeling of Cortisol’s Production, Metabolism, and Seasonal Variation
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DOI: 10.1177/0748730417729929
Abstract: Cortisol dynamics are governed by the integration of influences from the suprachiasmatic nucleus (SCN), the hypothalamic-pituitary-adrenal (HPA) axis, and metabolic enzymes, such as the 11β–hydroxysteroid dehydrogenase (HSD) family, which are highly expressed in hepatic and… read more here.
Keywords: renal axis; cortisol; hypothalamic pituitary; pituitary adrenal ... See more keywords
Adipose-Renal Axis in Diabetic Nephropathy.
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DOI: 10.2174/0929867329666220806115518
Abstract: Long-term diabetes can lead to renal injury known as diabetic nephropathy (DN), which is a major cause of end-stage renal disease (ESRD). However, its pathogenesis has not been well explained. Adipose tissue is recognized as… read more here.
Keywords: chemistry; adipose renal; axis diabetic; renal axis ... See more keywords
Mitochondrial Dysfunction in the Cardio-Renal Axis
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DOI: 10.3390/ijms24098209
Abstract: Cardiovascular disease (CVD) frequently complicates chronic kidney disease (CKD). The risk of all-cause mortality increases from 20% to 500% in patients who suffer both conditions; this is referred to as the so-called cardio-renal syndrome (CRS).… read more here.
Keywords: mitochondrial dysfunction; dysfunction cardio; cardio renal; renal axis ... See more keywords