Imaging Response to Contemporary Immuno-oncology Combination Therapies in Patients With Metastatic Renal Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.16379
Abstract: Key Points Question Do contemporary first-line therapy options for metastatic renal cell carcinoma (mRCC) have different likelihoods of objective imaging response (complete or partial response), and is objective imaging response associated with overall survival? Findings… read more here.
Keywords: oncology; cell carcinoma; renal cell; imaging response ... See more keywords
Adjuvant Therapy for Non-Clear Cell Renal Cell Carcinoma-The Ascent Continues.
Sign Up to like & getrecommendations! Published in 2024 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2024.25251
Abstract: Surgery is the preferred treatment for localized renal cell carcinoma (RCC). Although pursued with curative intent, approximately 50% of patients will experience disease recurrence. Pembrolizumab was approved as adjuvant treatment for patients at high risk… read more here.
Keywords: rcc; cell; cell carcinoma; clear cell ... See more keywords
Area Vulnerability and Disparities in Therapy for Patients With Metastatic Renal Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2024 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2024.8747
Abstract: This cohort study investigates associations between area-level measures of sociodemographic disadvantage and racial and ethnic disparities in receipt of systemic therapy for metastatic renal cell carcinoma among Medicare beneficiaries. read more here.
Keywords: cell carcinoma; metastatic renal; renal cell; area ... See more keywords
Cabozantinib as First-line Treatment in Patients With Metastatic Collecting Duct Renal Cell Carcinoma: Results of the BONSAI Trial for the Italian Network for Research in Urologic-Oncology (Meet-URO 2 Study).
Sign Up to like & getrecommendations! Published in 2022 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.0238
Abstract: Importance Metastatic collecting duct carcinoma (mCDC) is a rare type of non-clear cell renal cell carcinoma (ncRCC) with poor prognosis and no standard treatments. Despite retrospective series that have documented the benefit of cabozantinib in… read more here.
Keywords: renal cell; carcinoma; treatment; oncology ... See more keywords
Occupational disparities in tumor grade and cytosolic HMGB1 expression in renal cell cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Occupational Health"
DOI: 10.1002/1348-9585.12340
Abstract: We sought to examine occupational disparities in tumor grade and cytosolic expression of high‐mobility group box‐1 (HMGB1) among renal cell cancer (RCC) patients. read more here.
Keywords: grade cytosolic; renal cell; cell cancer; occupational disparities ... See more keywords
A group of novel VEGF splice variants as alternative therapeutic targets in renal cell carcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular oncology"
DOI: 10.1002/1878-0261.13401
Abstract: The efficacy of anti-angiogenic treatment by targeting VEGF/VEGF receptors in metastatic clear cell renal cell carcinoma (ccRCC) varies from patient to patient. Discovering the reasons behind this variability could lead to the identification of relevant… read more here.
Keywords: cell; renal cell; vegf; therapeutic targets ... See more keywords
APOBEC3C‐mediated NF‐κB activation enhances clear cell renal cell carcinoma progression
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13721
Abstract: Renowned as the predominant form of kidney cancer, clear cell renal cell carcinoma (ccRCC) exhibits susceptibility to immunotherapies due to its specific expression profile as well as notable immune cell infiltration. Despite this, effectively treating… read more here.
Keywords: cell renal; cell; cell carcinoma; clear cell ... See more keywords
Inhibition of EZH2 exerts antitumorigenic effects in renal cell carcinoma via LATS1
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13579
Abstract: The most common type of kidney cancer in adults is renal cell carcinoma (RCC), which accounts for approximately 90% of cases. RCC is a variant disease with numerous subtypes; the most common subtype is clear… read more here.
Keywords: cell carcinoma; cell; renal cell; ezh2 ... See more keywords
Single Atom‐Engineered 2D Catalytic Nanosheets for Sonocatalytic Suppression of Orthotopic Clear Cell Renal Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202414302
Abstract: Clear cell renal cell carcinoma (ccRCC), a prevalent malignant tumor, exhibits resistance to chemotherapy, necessitating advanced therapeutic approaches. Sonocatalytic therapy has emerged as a promising non‐invasive treatment for solid tumors due to its ability to… read more here.
Keywords: cell renal; cell; cell carcinoma; clear cell ... See more keywords
Addressable Peptide Self-Assembly on the Cancer Cell Membrane for Sensitizing Chemotherapy of Renal Cell Carcinoma.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201807175
Abstract: Chemotherapy has been validated unavailable for treatment of renal cell carcinoma (RCC) in clinic due to its intrinsic drug resistance. Sensitization of chemo-drug response plays a crucial role in RCC treatment and increase of patient… read more here.
Keywords: renal cell; cell membrane; cell carcinoma; cancer ... See more keywords
MARCO+ Tumor-Associated Macrophages Impede CD8+ T Cell Immunity to Facilitate Immunotherapy Resistance in Renal Cell Carcinoma.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202514600
Abstract: Immune checkpoint blockade (ICB) therapy, especially in combination regimens, has significantly increased survival of renal cell carcinoma (RCC) patients. However, the ICB‐resistant mechanisms remain largely unclear and require further investigation. Here, an immunosuppressive ecosystem in… read more here.
Keywords: cd8; cell; tumor; marco tumor ... See more keywords