Construction and validation of a prognostic model for kidney renal clear cell carcinoma based on podocyte-associated genes.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer medicine"
DOI: 10.1002/cam4.4733
Abstract: BACKGROUND As the most common renal malignancy, kidney renal clear cell carcinoma (KIRC) has a high prevalence and death rate as well as a poor response to treatment. Developing an efficient prognostic model is essential… read more here.
Keywords: prognostic model; kidney renal; podocyte associated; renal clear ... See more keywords
An immunometabolism‐related signature for renal clear cell carcinoma diagnosis and therapeutic target
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cell Communication and Signaling"
DOI: 10.1002/ccs3.70047
Abstract: Kidney renal clear cell carcinoma (KIRC) lacks sensitive early diagnostic markers and effective therapeutic guidance. Given the tight crosstalk between tumor metabolism and immunity, we investigated immunometabolism for biomarker discovery. Transcriptomes from The Cancer Genome… read more here.
Keywords: immunometabolism; renal clear; cell; cell carcinoma ... See more keywords
Mining TCGA database for screening and identification of hub genes in kidney renal clear cell carcinoma microenvironment
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29511
Abstract: To evaluate the diagnosis and prognosis of the tumor microenvironment (immunization and stromal cells) in kidney renal clear cell carcinoma (KIRC), KIRC cases selected from The Cancer Genome Atlas database were divided into two groups… read more here.
Keywords: microenvironment; renal clear; kidney renal; hub genes ... See more keywords
LAMTOR3 is a prognostic biomarker in kidney renal clear cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24648
Abstract: The objective of the study was to investigate the expression of LAMTOR3 in kidney renal clear cell carcinoma (KIRC) and its clinical significance. read more here.
Keywords: kidney renal; cell carcinoma; renal clear; clear cell ... See more keywords
JAK3 is a potential biomarker and associated with immune infiltration in kidney renal clear cell carcinoma.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106706
Abstract: Kidney renal clear cell carcinoma (KIRC) is one of the most common cancers globally, with an overall poor prognosis. The Janus kinase (JAK) family plays an essential role in cellular mechanisms such as proliferation, metastasis,… read more here.
Keywords: renal clear; kidney renal; biomarker; cell carcinoma ... See more keywords
Trigeminal ganglion metastasis of renal clear cell carcinoma: Cases reports and literature review.
Sign Up to like & getrecommendations! Published in 2019 at "World neurosurgery"
DOI: 10.1016/j.wneu.2019.04.230
Abstract: The trigeminal ganglion is an atypical site for metastasis, especially for renal clear cell carcinoma (RCC). We report two clinical cases of 66- and 58-year-old men with trigeminal symptoms. Both patients had a history of… read more here.
Keywords: renal clear; cell carcinoma; metastasis; clear cell ... See more keywords
Predictors of disease aggressiveness influence outcome from immunotherapy treatment in renal clear cell carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "OncoImmunology"
DOI: 10.1080/2162402x.2018.1500106
Abstract: ABSTRACT Renal clear cell carcinoma (RCC) is the most common type of kidney cancer and has a high propensity for metastasis. While treatment with immune checkpoint inhibitors, such as anti-PD-1, have shown modest improvements in… read more here.
Keywords: disease aggressiveness; cell carcinoma; treatment; clear cell ... See more keywords
Association of PD-L1, PD-L2, and Immune Response Markers in Matched Renal Clear Cell Carcinoma Primary and Metastatic Tissue Specimens
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Clinical Pathology"
DOI: 10.1093/ajcp/aqy141
Abstract: Objectives Immune checkpoint therapy has been promising in renal cell carcinoma, but no validated clinically relevant biomarkers exist. Metastatic deposits may have discordant biomarker expression. Methods Fifty matched pairs of primary and metastatic kidney tumors… read more here.
Keywords: primary metastatic; cell carcinoma; clear cell; renal clear ... See more keywords
Interaction between microglial cells and CD1C+ B dendritic cells leads to CD8+ T cells depletion during the early stages of renal clear cell carcinoma
Sign Up to like & getrecommendations! Published in 2024 at "Medicine"
DOI: 10.1097/md.0000000000038691
Abstract: Renal clear cell carcinoma (RCC) is a type of malignant tumor, which, in addition to surgical resection, radiotherapy, and chemotherapy, has been widely treated through immunotherapy recently. However, the influence of the tumor microenvironment and… read more here.
Keywords: cd8 cells; renal clear; cd1c dendritic; tumor ... See more keywords
Troponin T1 in tumorigenesis and immune modulation: Insights into multiple cancers and kidney renal clear cell carcinoma
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.18410
Abstract: Troponin T1 (TNNT1) plays a crucial role in muscle contraction but its role in cancer, particularly in kidney renal clear cell carcinoma (KIRC), is not well‐understood. This study explores the expression, clinical significance and biological… read more here.
Keywords: renal clear; kidney renal; cell; tumorigenesis immune ... See more keywords
Development of an Autophagy-Related Gene Prognostic Model and Nomogram for Estimating Renal Clear Cell Carcinoma Survival
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Oncology"
DOI: 10.1155/2021/8810849
Abstract: Background Kidney renal clear cell carcinoma (KIRC) is a fatal malignancy of the urinary system. Autophagy is implicated in KIRC occurrence and development. Here, we evaluated the prognostic value of autophagy-related genes (ARGs) in kidney… read more here.
Keywords: cell carcinoma; analysis; clear cell; renal clear ... See more keywords