Articles with "renal clearable" as a keyword



A Renal-Clearable Activatable Molecular Probe for Fluoro-Photacoustic and Radioactive Imaging of Cancer Biomarkers.

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Published in 2022 at "Small"

DOI: 10.1002/smll.202201334

Abstract: In vivo simultaneous visualization of multiple biomarkers is critical to accurately diagnose disease and decipher fundamental processes at a certain pathological evolution, which however is rarely exploited. Herein, a multimodal activatable imaging probe (P-125 I)… read more here.

Keywords: renal clearable; prostate cancer; clearable activatable; psma ... See more keywords

Renal Clearable Nanodots-Engineered Erythrocytes with Enhanced Circulation and Tumor Accumulation for Photothermal Therapy of Hepatocellular Carcinoma.

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Published in 2024 at "Small"

DOI: 10.1002/smll.202309278

Abstract: Living cell-mediated nanodelivery system is considered a promising candidate for targeted antitumor therapy; however, their use is restricted by the adverse interactions between carrier cells and nanocargos. Herein, a novel erythrocyte-based nanodelivery system is developed… read more here.

Keywords: renal clearable; system; nanodelivery system; hepatocellular carcinoma ... See more keywords

Renal-Clearable Probe with Water Solubility and Photostability for Biomarker-Activatable Detection of Acute Kidney Injuries via NIR-II Fluorescence and Optoacoustic Imaging.

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Published in 2023 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.3c00956

Abstract: Acute kidney injuries (AKI) have serious short-term or long-term complications with high morbidity and mortality rate, thus posing great health threats. Developing high-performance NIR-II probes for noninvasive in situ detection of AKI via NIR-II fluorescent… read more here.

Keywords: renal clearable; biomarker; kidney; detection ... See more keywords

Renal-Clearable Metalloporphyrin Complex-Based Nanosonosensitizers Using Photoacoustic Imaging Guiding to Enhance Sonodynamic Cancer Therapy.

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Published in 2025 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.4c21982

Abstract: Sonodynamic therapy (SDT) is a noninvasive approach to tumor treatment, with ongoing efforts being focused on developing highly effective sonosensitizers with low toxicity. Herein, a liquid-phase stripping technique was introduced as a simple reflux method… read more here.

Keywords: renal clearable; cancer; photoacoustic imaging; therapy ... See more keywords

Facile and Controllable Synthesis of the Renal-Clearable "Luminous Pearls" for in Vivo Afterglow/Magnetic Resonance Imaging.

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Published in 2021 at "ACS nano"

DOI: 10.1021/acsnano.1c07243

Abstract: To date, the strategic exploration of a synthetic approach to afford persistent luminescent nanoparticles (PLNPs) integrated with precisely controlled size/monodispersity and renal-clearable capability remains extremely challenging. Herein, we report a facile synthetic process with an… read more here.

Keywords: size; afterglow magnetic; magnetic resonance; synthesis ... See more keywords

Intratumoral self-assembly of renal-clearable gold nanoparticles as precise photothermal nanomedicine for liver tumor therapy

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Published in 2025 at "Science Advances"

DOI: 10.1126/sciadv.adw7032

Abstract: Noninvasive photothermal therapy (PTT) for cancer with photothermal agents (PTAs) has recently achieved success in both preclinical and clinical trials. However, traditional PTAs tend to nonspecifically accumulate in normal liver tissue, hampering their use in… read more here.

Keywords: renal clearable; intratumoral self; tumor; self assembly ... See more keywords

Renal clearable CRISPR nanosensor targeting mitochondrial DNA mutation for noninvasive monitoring of tumor progression and metastasis

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Published in 2025 at "Science Advances"

DOI: 10.1126/sciadv.adz4594

Abstract: Mitochondrial DNA (mtDNA) mutations are emerging as important molecular features of tumorigenesis. Liquid biopsies, involving analysis of cell-free mtDNA, enable early cancer detection but suffer from low sensitivity due to scarce analytes. Here, we developed… read more here.

Keywords: monitoring tumor; renal clearable; tumor progression; progression metastasis ... See more keywords