Design, Synthesis, and Bioactivity Investigation of Cyclic Lipopeptide Antibiotics Containing Eight to Nine Amino Acids.
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DOI: 10.1021/acs.jmedchem.2c01344
Abstract: The current global issue of antibiotic resistance is serious, and there is an urgent requirement of developing novel antibiotics. Octapeptins have recently regained interest because of their activities against resistant Gram-negative bacteria. We synthesized four… read more here.
Keywords: cyclic lipopeptide; activity; synthesis; renal cytotoxicity ... See more keywords