Protein arginine methyltransferases in renal development, injury, repair, and fibrosis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1123415
Abstract: Protein arginine methyltransferases (PRMTs) methylate a range of histone and non-histone substrates and participate in multiple biological processes by regulating gene transcription and post-translational modifications. To date, most studies on PRMTs have focused on their… read more here.
Keywords: protein arginine; repair fibrosis; arginine methyltransferases; development injury ... See more keywords
Zebrafish Model-Based Assessment of Indoxyl Sulfate-Induced Oxidative Stress and Its Impact on Renal and Cardiac Development
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11020400
Abstract: Kidney disease patients may have concurrent chronic kidney disease-associated mineral bone disorder and hypertension. Cardiovascular disease (CVD) and neuropathy occur due to kidney failure-induced accumulation of uremic toxins in the body. Indoxyl sulfate (IS), a… read more here.
Keywords: indoxyl sulfate; cardiac renal; development; renal development ... See more keywords
Sex-Specificity of Mineralocorticoid Target Gene Expression during Renal Development, and Long-Term Consequences
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18020457
Abstract: Sex differences have been identified in various biological processes, including hypertension. The mineralocorticoid signaling pathway is an important contributor to early arterial hypertension, however its sex-specific expression has been scarcely studied, particularly with respect to… read more here.
Keywords: gene expression; target; mineralocorticoid; renal development ... See more keywords