Cystic renal‐epithelial derived induced pluripotent stem cells from polycystic kidney disease patients
Sign Up to like & getrecommendations! Published in 2020 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.18-0283
Abstract: Autosomal‐dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease, leading to kidney failure in most patients. In approximately 85% of cases, the disease is caused by mutations in PKD1. How dysregulation of… read more here.
Keywords: kidney; cystic renal; stem cells; renal epithelial ... See more keywords
Generation of Human Induced Pluripotent Stem Cells from Renal Epithelial Cells.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/7651_2021_419
Abstract: In the past decades, human induced pluripotent stem cells (iPSCs) have been generated by the ectopic expression of "Yamanaka factors" in multiple somatic cells. However, the procedure to get access to donor cells is hard… read more here.
Keywords: human induced; pluripotent stem; induced pluripotent; stem ... See more keywords
RORA alleviates LPS-induced apoptosis of renal epithelial cells by promoting PGC-1α transcription
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-022-02184-2
Abstract: To explore the effect of RORA on LPS-induced renal epithelial cell apoptosis and the underlying mechanism. LPS-treated HK-2 cells were established as a cellular model of acute kidney injury. The expression of RORA or/and PGC-1α… read more here.
Keywords: rora; apoptosis; rora pgc; renal epithelial ... See more keywords
In vivo analysis of renal epithelial cells in zebrafish.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in cell biology"
DOI: 10.1016/bs.mcb.2019.04.016
Abstract: The zebrafish kidney has been used effectively for studying kidney development, repair and disease. New gene editing capability makes it a more versatile in vivo vertebrate model system to investigate renal epithelial cells in their… read more here.
Keywords: vivo analysis; biology; cells zebrafish; analysis renal ... See more keywords
Substrate curvature affects the shape, orientation, and polarization of renal epithelial cells.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.07.019
Abstract: The unique structure of kidney tubules is representative of their specialized function. Because maintaining tubular structure and controlled diameter is critical for kidney function, it is critical to understand how topographical cues, such as curvature,… read more here.
Keywords: polarization; morphology; substrate curvature; cell ... See more keywords
Nutritionally Available Selenocysteine Derivative Antagonizes Cisplatin-Induced Toxicity in Renal Epithelial Cells through Inhibition of Reactive Oxygen Species-Mediated Signaling Pathways.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.8b01876
Abstract: Discovery of nutritionally available agents that could antagonize cisplatin-induced nephrotoxicity is of great significance and clinical application potential. 3,3'-Diselenodipropionic acid (DSePA) is a seleno-amino acid derivative that exhibits strong antioxidant activity. Therefore, this study aimed… read more here.
Keywords: epithelial cells; cisplatin; nutritionally available; induced toxicity ... See more keywords
Effect of Crystal Shape and Aggregation of Calcium Oxalate Monohydrate on Cellular Toxicity in Renal Epithelial Cells
Sign Up to like & getrecommendations! Published in 2017 at "ACS Omega"
DOI: 10.1021/acsomega.7b00510
Abstract: Renal epithelial cell injury is a key step in inducing kidney stone formation. This injury induced by crystallites with different shapes and aggregation states has been receiving minimal research attention. To compare the shape and… read more here.
Keywords: aggregation; epithelial cells; toxicity; calcium oxalate ... See more keywords
Simvastatin reduces the carcinogenic effect of 3-methylcholanthrene in renal epithelial cells through histone deacetylase 1 inhibition and RhoA reactivation
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-40757-6
Abstract: The therapeutic effects of simvastatin for renal cell carcinoma (RCC) are controversial. In this study, the effects of simvastatin on the carcinogenic properties of 3-methylcholanthrene (3MC; an aryl-hydrocarbon receptor [AhR] agonist) in human renal epithelial… read more here.
Keywords: epithelial cells; rhoa; histone deacetylase; expression ... See more keywords
Activated SOX9+ renal epithelial cells promote kidney repair through secreting factors
Sign Up to like & getrecommendations! Published in 2023 at "Cell Proliferation"
DOI: 10.1111/cpr.13394
Abstract: A broad spectrum of lethal kidney diseases involves the irreversible destruction of the tubular structures, leading to renal function loss. Following injury, a spectrum of tissue‐resident epithelial stem/progenitor cells are known to be activated and… read more here.
Keywords: sox9 renal; kidney; sox9 recs; renal epithelial ... See more keywords
Carbonic anhydrase IX (CA9) expression in multiple renal epithelial tumour subtypes
Sign Up to like & getrecommendations! Published in 2020 at "Histopathology"
DOI: 10.1111/his.14204
Abstract: Renal epithelial neoplasms (RENs) can be difficult to subclassify, owing to overlapping morphological features. Carbonic anhydrase 9 (CA9) is a common biomarker for clear cell renal cell carcinoma (CCRCC); however, the sensitivity and specificity across… read more here.
Keywords: carbonic anhydrase; anhydrase ca9; ca9 expression; renal epithelial ... See more keywords
Establishment, Persistence, and Reactivation of Latent HIV-1 Infection in Renal Epithelial Cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.00624-22
Abstract: Anti-retroviral therapy (ART) has dramatically reduced HIV-related morbidity and mortality. Despite this success, a number of challenges remain, including the long-term persistence of multiple, clinically latent viral reservoirs capable of reactivation in the absence of… read more here.
Keywords: persistence; hiv; rte cells; reactivation ... See more keywords