Renal globotriaosylceramide facilitates tubular albumin absorption and its inhibition protects against acute kidney injury.
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DOI: 10.1016/j.kint.2019.02.010
Abstract: To elucidate the physiologic function of renal globotriaosylceramide (Gb3/CD77), which up-to-date has been associated exclusively with Shiga toxin binding, we have analyzed renal function in Gb3-deficient mice. Gb3 synthase KO (Gb3S-/-) mice displayed an increased… read more here.
Keywords: mice; gb3; kidney injury; renal globotriaosylceramide ... See more keywords