LPS ameliorates renal ischemia/reperfusion injury via Hsp27 up-regulation
Sign Up to like & getrecommendations! Published in 2017 at "International Urology and Nephrology"
DOI: 10.1007/s11255-017-1735-3
Abstract: PurposeWe have recently reported lipopolysaccharide (LPS) pretreatment attenuated renal ischemia/reperfusion injury (IRI), but the exact mechanism remains to be well elucidated. It was reported that heat shock protein (Hsp) 27 was up-regulated after administration of… read more here.
Keywords: hsp27 regulation; renal ischemia; hsp27; iri ... See more keywords
Molecular mechanisms of ferroptosis in renal ischemia-reperfusion injury Investigated via bioinformatics analysis and animal experiments
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Investigative Medicine"
DOI: 10.1177/10815589241288518
Abstract: Kidney transplantation is a pivotal treatment for end-stage renal disease. However, renal ischemia-reperfusion injury (IRI) during surgery significantly impacts graft function. Despite unclear molecular mechanisms, no specific therapies or preventative measures are available. Gene expression… read more here.
Keywords: animal experiments; ferroptosis; renal iri; network ... See more keywords
Network Pharmacology-Based Exploration of the Therapeutic Mechanisms of Cordyceps cicadae in Renal Ischemia/Reperfusion
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Transplantation"
DOI: 10.12659/aot.937469
Abstract: Background Cordyceps cicadae is beneficial in treating renal diseases, especially in inhibiting renal ischemia/reperfusion injury (IRI). The aim of this study was to systematically analyze and predict the potential mechanism of Cordyceps cicadae in renal… read more here.
Keywords: pharmacology; cordyceps cicadae; renal iri; network pharmacology ... See more keywords
Enhancement of YTHDF2 plays a protective role in acute IRI models through downregulation of TUG1 expression
Sign Up to like & getrecommendations! Published in 2025 at "PLOS One"
DOI: 10.1371/journal.pone.0319605
Abstract: As one of the major causes of acute kidney injury, renal ischemia-reperfusion is a common health problem in a series of clinical situations, including renal transplantation. Although the mechanisms of renal IRI have been widely… read more here.
Keywords: iri models; iri; acute iri; role ... See more keywords
IL-38 attenuates renal ischemia/reperfusion injury through suppressing inflammation in mice.
Sign Up to like & getrecommendations! Published in 2025 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2025.70.1.4
Abstract: Inflammation plays an important role in the pathogenesis of renal ischemia/reperfusion injury (IRI). Interleukin-38 (IL-38) is an emerging cytokine with multiple functions involved in infection and immunity. The present study aimed to determine whether IL-38… read more here.
Keywords: renal ischemia; ischemia reperfusion; iri; reperfusion injury ... See more keywords
miR-25-3p protects renal tubular epithelial cells from apoptosis induced by renal IRI by targeting DKK3
Sign Up to like & getrecommendations! Published in 2021 at "Open Life Sciences"
DOI: 10.1515/biol-2021-0127
Abstract: Abstract Renal ischemia-reperfusion injury (IRI) is one of the main causes of acute kidney injury (AKI). So far, there have been many studies on renal IRI, although an effective treatment method has not been developed.… read more here.
Keywords: mir protects; dkk3; mir; apoptosis ... See more keywords
VASPIN reduces inflammation and endoplasmic reticulum stress of renal tubular epithelial cells by inhibiting HMGB1 and relieves renal ischemia-reperfusion injury.
Sign Up to like & getrecommendations! Published in 2020 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202009_22839
Abstract: OBJECTIVE Renal ischemia-reperfusion injury (IRI) is a clinically common issue and the resulting acute kidney injury (AKI) seriously threatens the patient's life. Therefore, prevention and treatment of renal IRI are the key to alleviating AKI… read more here.
Keywords: epithelial cells; iri; renal iri; tubular epithelial ... See more keywords
Recent Advances of MSCs in Renal IRI: From Injury to Renal Fibrosis
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DOI: 10.3390/bioengineering11050432
Abstract: Renal fibrosis is a pathological endpoint of maladaptation after ischemia-reperfusion injury (IRI), and despite many attempts, no good treatment has been achieved so far. At the core of renal fibrosis is the differentiation of various… read more here.
Keywords: mscs renal; fibrosis; renal fibrosis; recent advances ... See more keywords
Different Acute Kidney Injury Patterns after Renal Ischemia Reperfusion Injury and Extracorporeal Membrane Oxygenation in Mice
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231911000
Abstract: The use of extracorporeal membrane oxygenation (ECMO) is associated with acute kidney injury (AKI) in thoracic organ transplantation. However, multiple other factors contribute to AKI development after these procedures such as renal ischemia-reperfusion injury (IRI)… read more here.
Keywords: renal iri; kidney; kidney injury; injury patterns ... See more keywords
Role of prostaglandin E2 receptor 4 in the modulation of apoptosis and mitophagy during ischemia/reperfusion injury in the kidney.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular medicine reports"
DOI: 10.3892/mmr.2019.10576
Abstract: The mechanisms by which prostaglandin E2 receptor 4 (EP4) protects against renal ischemia‑reperfusion (I/R) injury (IRI) remain to be fully elucidated. In the present study, the protective effects of EP4 signaling on renal mitochondria and… read more here.
Keywords: prostaglandin receptor; iri; renal iri; mitochondrial autophagy ... See more keywords