MicroRNA‐194 overexpression protects against hypoxia/reperfusion‐induced HK‐2 cell injury through direct targeting Rheb
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28114
Abstract: Renal ischemia‐reperfusion injury, a major cause of renal failure, always leads to acute kidney injury and kidney fibrosis. MicroRNAs (miRs) have been reported to be associated with renal ischemia‐reperfusion injury. miR‐194 was downregulated following renal… read more here.
Keywords: renal ischemia; ischemia reperfusion; reperfusion injury; injury ... See more keywords
Artesunate Inhibits Renal Ischemia Reperfusion-Stimulated Lung Inflammation in Rats by Activating HO-1 Pathway
Sign Up to like & getrecommendations! Published in 2017 at "Inflammation"
DOI: 10.1007/s10753-017-0669-3
Abstract: ABSTRACTArtesunate (AS), a semi-synthetic derivative of Artemisia, has been shown to exert a wide range of pharmacological effects, such as anti-inflammatory and antioxidant functions. However, the protective functions of AS on renal ischemia reperfusion injury… read more here.
Keywords: biochemistry; stimulated lung; renal ischemia; inflammation ... See more keywords
LPS ameliorates renal ischemia/reperfusion injury via Hsp27 up-regulation
Sign Up to like & getrecommendations! Published in 2017 at "International Urology and Nephrology"
DOI: 10.1007/s11255-017-1735-3
Abstract: PurposeWe have recently reported lipopolysaccharide (LPS) pretreatment attenuated renal ischemia/reperfusion injury (IRI), but the exact mechanism remains to be well elucidated. It was reported that heat shock protein (Hsp) 27 was up-regulated after administration of… read more here.
Keywords: hsp27 regulation; renal ischemia; hsp27; iri ... See more keywords
Renal-targeting peptide-microRNA nanocomplex for near IR imaging and therapy of renal ischemia/reperfusion injury
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Industrial and Engineering Chemistry"
DOI: 10.1016/j.jiec.2021.02.007
Abstract: Abstract Renal ischemia-reperfusion injury (RI/R) is one of the main causes of acute renal injury and a common clinical disease with high morbidity and mortality. It is of great significance to deliver microRNAs (miRNAs) to… read more here.
Keywords: injury; renal ischemia; reperfusion injury; ischemia reperfusion ... See more keywords
The C5a/C5aR1 axis promotes progression of renal tubulointerstitial fibrosis in a mouse model of renal ischemia/reperfusion injury.
Sign Up to like & getrecommendations! Published in 2019 at "Kidney international"
DOI: 10.1016/j.kint.2019.01.039
Abstract: C5a is a potent proinflammatory agonist that mediates renal ischemia reperfusion (IR) injury, but the potential for modulating chronic post-ischemic fibrosis and use of therapeutic antagonist are undefined. Here we determine whether C5a receptor 1… read more here.
Keywords: renal ischemia; c5a; fibrosis; c5ar1 ... See more keywords
Renal ischemia/reperfusion injury: An insight on in vitro and in vivo models.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117860
Abstract: Optimal tissue oxygenation is essential for its normal function. Suboptimal oxygenation or ischemia contributes to increased mortalities during various pathological conditions such as stroke, acute kidney injury (AKI), cardiac failure. Despite the rapid progression of… read more here.
Keywords: renal ischemia; vitro vivo; vivo models; iri ... See more keywords
Structural and functional disorders of hippocampus following ischemia/reperfusion in lower limbs and kidneys
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2017.06.058
Abstract: Recent evidence suggests that ischemia/reperfusion (I/R) in an organ may have distance effect on the brain. In this study, the effects of renal I/R, limb I/R or both together on the structural and function of… read more here.
Keywords: renal ischemia; limb; reperfusion; ischemia ... See more keywords
Kappa-opioid receptor agonist U50448H protects against renal ischemia-reperfusion injury in rats via activating the PI3K/Akt signaling pathway
Sign Up to like & getrecommendations! Published in 2018 at "Acta Pharmacologica Sinica"
DOI: 10.1038/aps.2017.51
Abstract: Renal ischemia-reperfusion injury (IRI) is regarded as a leading cause of acute kidney failure and renal dysfunction. Previous studies show that kappa opioid receptor (KOR) agonists can attenuate IRI in cardiomycytes and neuronal cells. In… read more here.
Keywords: akt; renal ischemia; agonist u50448h; iri ... See more keywords
Pharmacologic targeting of renal ischemia-reperfusion injury using a normothermic machine perfusion platform
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-63687-0
Abstract: Normothermic machine perfusion (NMP) is an emerging modality for kidney preservation prior to transplantation. NMP may allow directed pharmacomodulation of renal ischemia-reperfusion injury (IRI) without the need for systemic donor/recipient therapies. Three proven anti-IRI agents… read more here.
Keywords: renal ischemia; perfusion; normothermic machine; iri ... See more keywords
The Effects of Quercetin on Apoptosis and Antioxidant Activity in a Renal Ischemia/Reperfusion Injury Animal Model
Sign Up to like & getrecommendations! Published in 2022 at "Drug Research"
DOI: 10.1055/a-1999-7600
Abstract: Abstract Renal ischemia-reperfusion injury (IRI) is considered as one of the most prevalent causes of acute kidney injury (AKI), which can happen in various clinical situations including hypovolemic shock, injury, thrombo-embolism, and after a kidney… read more here.
Keywords: reperfusion injury; effects quercetin; reperfusion; injury ... See more keywords
Isoflurane Increases Tolerance to Renal Ischemia Reperfusion Injury Compared to Propofol: An Experimental Study in Pigs
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Investigative Surgery"
DOI: 10.1080/08941939.2019.1637038
Abstract: Abstract Purpose: To compare two clinically relevant anesthetic agents, i.e., isoflurane versus propofol with respect to protection of the kidney in a porcine renal ischemia reperfusion model. Materials and Methods: 14 hybrid pigs were randomized… read more here.
Keywords: renal ischemia; reperfusion; isoflurane; ischemia reperfusion ... See more keywords