ABLATE: a score to predict complications and recurrence rate in percutaneous treatments of renal lesions
Sign Up to like & getrecommendations! Published in 2020 at "Medical Oncology"
DOI: 10.1007/s12032-020-01351-3
Abstract: RENAL score has been validated on predicting adverse events and relapses in percutaneous treatments of renal lesions. To better fit interventional issues a modified score (mRENAL) has been introduced, but the only difference from the… read more here.
Keywords: renal lesions; treatments renal; renal mrenal; ablate score ... See more keywords
Assessment of Tuberous Sclerosis Complex Associated With Renal Lesions by Targeted Next-generation Sequencing in Mainland China.
Sign Up to like & getrecommendations! Published in 2017 at "Urology"
DOI: 10.1016/j.urology.2016.10.056
Abstract: OBJECTIVE To identify the TSC1 and TSC2 mutations in patients with tuberous sclerosis complex (TSC) associated with renal lesions, and to explore the relationship between genotypes and phenotypes. MATERIALS AND METHODS We analyzed 43 individuals… read more here.
Keywords: associated renal; tuberous sclerosis; renal lesions; sclerosis complex ... See more keywords
Virtual Unenhanced Images at Dual-Energy CT: Influence on Renal Lesion Characterization.
Sign Up to like & getrecommendations! Published in 2019 at "Radiology"
DOI: 10.1148/radiol.2019181100
Abstract: Background Dual-energy (DE) CT allows reconstruction of virtual noncontrast (VNC) images from a single-phase contrast agent-enhanced examination, potentially reducing the need for multiphasic CT to characterize renal lesions. However, data regarding diagnostic performance of VNC… read more here.
Keywords: lesion characterization; unenhanced images; renal lesions; vnc ... See more keywords
Signaling pathways predisposing to chronic kidney disease progression.
Sign Up to like & getrecommendations! Published in 2020 at "JCI insight"
DOI: 10.1172/jci.insight.126183
Abstract: The loss of functional nephrons after kidney injury triggers the compensatory growth of the remaining ones to allow functional adaptation. However, in some cases, these compensatory events activate signaling pathways that lead to pathological alterations… read more here.
Keywords: signaling pathways; renal lesions; chronic kidney; ifn response ... See more keywords
Analysis of renal lesions in Chinese tuberous sclerosis complex patients with different types of TSC gene mutations
Sign Up to like & getrecommendations! Published in 2022 at "Genetics and Molecular Biology"
DOI: 10.1590/1678-4685-gmb-2020-0387
Abstract: Abstract We sought to explore the relationship between renal lesion features and genetic mutations in tuberous sclerosis complex (TSC) patients. TSC patients with renal lesions were subjected to TSC1/2 gene next-generation sequencing (NGS). TSC1/2 mutation… read more here.
Keywords: tsc gene; renal lesions; patients different; gene ... See more keywords
Histopathological findings of renal tissue induced by oxidative stress due to different concentrations of fluoride.
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.17365
Abstract: It has been reported that excessive intake of fluoride can induce renal lesions. However, its pathogenesis is still less understood. Therefore, this study was conducted to investigate oxidative damage and the relationships between the oxidative… read more here.
Keywords: renal lesions; histopathological findings; oxidative damage; induced renal ... See more keywords
Defining the Magnetic Resonance Features of Renal Lesions and Their Response to Everolimus in a Transgenic Mouse Model of Tuberous Sclerosis Complex
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.851192
Abstract: Tuberous sclerosis complex (TSC) is an inherited genetic disorder characterized by mutations in TSC1 or TSC2 class of tumor suppressers which impact several organs including the kidney. The renal manifestations are usually in the form… read more here.
Keywords: magnetic resonance; renal lesions; therapy; response ... See more keywords
Renal Lesions and Nephrotoxicity: Contemporary Challenges and Future Directions
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24087015
Abstract: Renal lesions and nephrotoxicity are major challenges for researchers and patients alike [...]. read more here.
Keywords: lesions nephrotoxicity; renal lesions; challenges future; contemporary challenges ... See more keywords