Liraglutide treatment attenuates inflammation markers in the cardiac, cerebral and renal microvasculature in streptozotocin‐induced diabetic rats
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DOI: 10.1111/eci.13807
Abstract: Diabetes mellitus (DM) induces cardiac and cerebral microvascular dysfunction via increased glycation, oxidative stress and endothelial activation. Liraglutide, a glucagon‐like peptide‐1 analogue, inhibited NOX2 and adhesion molecules in isolated endothelial cells. Here, we have studied… read more here.
Keywords: renal microvasculature; cardiac cerebral; diabetic rats; cerebral renal ... See more keywords
Effect of Calcitriol on the Renal Microvasculature Differentiation Disturbances Induced by AT1 Blockade During Nephrogenesis in Rats
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DOI: 10.3389/fmed.2020.00023
Abstract: Alterations in the renal vasculature during fetal programming can cause disturbances in renal structure and function that persist into adulthood. Calcitriol can affect cellular differentiation and proliferation, and promote endothelial cell maintenance, each of which… read more here.
Keywords: at1 blockade; microvasculature differentiation; renal microvasculature; calcitriol ... See more keywords
Elastin haploinsufficiency accelerates age-related structural and functional changes in the renal microvasculature and impairment of renal hemodynamics in female mice
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DOI: 10.3389/fphys.2023.1141094
Abstract: Age-related decline in functional elastin is associated with increased arterial stiffness, a known risk factor for developing cardiovascular disease. While the contribution of elastin insufficiency to the stiffening of conduit arteries is well described, little… read more here.
Keywords: renal microvasculature; age related; pressure; changes renal ... See more keywords