Renal mitochondrial injury in the pathogenesis of CKD: mtDNA and mitomiRs.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical science"
DOI: 10.1042/cs20210512
Abstract: Chronic kidney disease (CKD) is a public health concern that affects over 200 million people worldwide and is associated with a tremendous economic burden. Therefore, deciphering the mechanisms underpinning CKD is crucial to decelerate its… read more here.
Keywords: ckd; mitochondrial injury; pathogenesis; renal mitochondrial ... See more keywords
Yiqi Huoxue Tongluo recipe regulates NR4A1 to improve renal mitochondrial function in unilateral ureteral obstruction (UUO) rats
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DOI: 10.1080/13880209.2022.2148168
Abstract: Abstract Context Yiqi Huoxue Tongluo recipe (YHTR) is a traditional Chinese medicine for the treatment of chronic kidney disease, but its exact mechanism is not clear. Objectives To monitor the potential improvement of renal mitochondrial… read more here.
Keywords: yiqi huoxue; mitochondrial function; renal mitochondrial; huoxue tongluo ... See more keywords
Urinary mitochondrial DNA level is an indicator of intra-renal mitochondrial depletion and renal scarring in diabetic nephropathy
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DOI: 10.1093/ndt/gfx339
Abstract: Background Mitochondrial dysfunction plays an important role in the pathogenesis and progression of diabetic nephropathy (DN). We study the relation between urinary and intra-renal mitochondrial deoxyribonucleic acid (mtDNA) levels and renal dysfunction in DN. Methods… read more here.
Keywords: intra renal; mtdna; level; renal mitochondrial ... See more keywords
circMTND5 Participates in Renal Mitochondrial Injury and Fibrosis by Sponging MIR6812 in Lupus Nephritis
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DOI: 10.1155/2022/2769487
Abstract: Recent studies have focused on nuclear-encoded circular RNAs (circRNAs) in kidney diseases, but little is known about mitochondrial circRNAs. Differentially expressed circRNAs were analyzed by RNA deep sequencing from lupus nephritis (LN) biopsies and normal… read more here.
Keywords: circmtnd5; expression; lupus nephritis; mitochondrial injury ... See more keywords