Effect of rMnSOD on Sodium Reabsorption in Renal Proximal Tubule in Ochratoxin A—Treated Rats
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26197
Abstract: Ochratoxin A (OTA) is a mycotoxin produced by Aspergillus and Penicillium that represent toxic real threat for human beings and animal health. In this study we evaluated the effect of a new recombinant mitochondrial manganese… read more here.
Keywords: renal proximal; reabsorption renal; reabsorption; proximal tubule ... See more keywords
CCDC158: A novel regulator in renal proximal tubular endocytosis unveiled through exome sequencing and interactome analysis
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.31447
Abstract: Renal proximal tubular reabsorption of proteins and polypeptides is tightly regulated by a concerted action of the multi‐ligand receptors with subsequent processing from the clathrin‐coated pits to early/recycling and late endosomes and towards lysosomes. We… read more here.
Keywords: endocytosis; ccdc158; proximal tubular; tubular endocytosis ... See more keywords
Preconditioning of primary human renal proximal tubular epithelial cells without tryptophan increases survival under hypoxia by inducing autophagy
Sign Up to like & getrecommendations! Published in 2017 at "International Urology and Nephrology"
DOI: 10.1007/s11255-017-1596-9
Abstract: PurposeHypoxia plays a significant role in the pathogenesis of acute kidney injury (AKI). Autophagy protects from AKI. Amino acid deprivation induces autophagy. The effect of l-tryptophan depletion on survival and autophagy in cultures of renal… read more here.
Keywords: renal proximal; without tryptophan; tryptophan; autophagy ... See more keywords
Fatty acids bound to albumin induce prostaglandin E2 production in human renal proximal tubular epithelial cell line HK-2.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.07.033
Abstract: Fatty acids bound to albumin have been reported to be involved in various responses in renal proximal tubular cells following albumin overload, leading to progression of tubulointerstitial damage in the kidneys. In addition, it has… read more here.
Keywords: renal proximal; production; fatty acids; bound albumin ... See more keywords
Novel Role of Hemeoxygenase-1 in Phthalate-Induced Renal Proximal Tubule Cell Ferroptosis.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c07762
Abstract: Phthalates are widely used to improve the flexibility of poly(vinyl chloride) (PVC) polymer agriculture products. Di(2-ethylhexyl) phthalate (DEHP) is a type of addition to plastic and can lead to many health problems. Hemeoxygenase-1 (HO-1) is… read more here.
Keywords: renal proximal; tubule cell; induced renal; ferroptosis ... See more keywords
Vitamin K2 Attenuates Mitochondrial Damage in Renal Proximal Tubular Cells.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.5c01320
Abstract: Excessive reactive oxygen species (ROS) levels cause oxidative stress, which can lead to various diseases. Renal failure is associated with oxidative stress and mitochondrial dysfunction. Vitamin K1 (phylloquinone) and K2 (menaquinone) are essential for blood… read more here.
Keywords: renal proximal; damage; tubular cells; oxidative stress ... See more keywords
Canagliflozin protects against cisplatin-induced acute kidney injury by AMPK-mediated autophagy in renal proximal tubular cells
Sign Up to like & getrecommendations! Published in 2022 at "Cell Death Discovery"
DOI: 10.1038/s41420-021-00801-9
Abstract: Sodium-glucose cotransporter 2 inhibitors, which are recently introduced as glucose-lowering agents, improve cardiovascular and renal outcomes in patients with diabetes mellitus. These drugs also have beneficial effects in various kidney disease models. However, the effect… read more here.
Keywords: canagliflozin protects; canagliflozin; protects cisplatin; renal proximal ... See more keywords
Mitochondrial Transplantation Therapy against Ifosfamide Induced Toxicity on Rat Renal Proximal Tubular Cells
Sign Up to like & getrecommendations! Published in 2022 at "Drug Research"
DOI: 10.1055/a-1967-2066
Abstract: Abstract Mitochondrial dysfunction is a basic mechanism leading to drug nephrotoxicity. Replacement of defective mitochondria with freshly isolated mitochondria is potentially a comprehensive tool to inhibit cytotoxicity induced by ifosfamide on renal proximal tubular cells… read more here.
Keywords: renal proximal; rptcs; rat; mitochondrial transplantation ... See more keywords
The influence of fasudil on renal proximal tubular cell epithelial–mesenchymal transition induced by parathormone
Sign Up to like & getrecommendations! Published in 2017 at "Renal Failure"
DOI: 10.1080/0886022x.2017.1349677
Abstract: Abstract Background: Renal fibrosis is a common pathway through which a variety of chronic kidney diseases progress to end-stage renal disease. Epithelial–mesenchymal transition (EMT) of renal proximal tubular cells is one of the most important… read more here.
Keywords: mesenchymal transition; epithelial mesenchymal; renal proximal; proximal tubular ... See more keywords
Actoeside mitigated the renal proximal tubule cells damage triggered by high glucose through miR-766/VCAM1/NF-κB signalling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of physiology and biochemistry"
DOI: 10.1080/13813455.2021.1920983
Abstract: CONTEXT Diabetic nephropathy (DN) triggered by diabetes mellitus is one of the primary causes of end-stage renal failure worldwide. OBJECTIVE This study intends to explore the function and potential mechanism of actoeside on renal proximal… read more here.
Keywords: cells damage; mir 766; renal proximal; 766 vcam1 ... See more keywords
Anti-EMT and anti-fibrosis effects of protocatechuic aldehyde in renal proximal tubular cells and the unilateral ureteral obstruction animal model
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2022.2088809
Abstract: Abstract Context Protocatechuic aldehyde (PCA) is a natural product that has various benefits for fibrosis. Objective This study evaluated the effects of PCA on renal fibrosis. Materials and methods Epithelial–mesenchymal transition (EMT) was induced by… read more here.
Keywords: renal proximal; proximal tubular; pca; unilateral ureteral ... See more keywords