Tenofovir alafenamide is associated with improved alanine aminotransferase and renal safety compared to tenofovir disoproxil fumarate
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27863
Abstract: Tenofovir alafenamide (TAF) is a novel prodrug of tenofovir for the treatment of chronic hepatitis B (CHB) infection. We aimed to evaluate the impact of switching to TAF on alanine aminotransferase (ALT) normalization and renal… read more here.
Keywords: safety; alanine aminotransferase; renal safety; tenofovir disoproxil ... See more keywords
The renal safety and efficacy of combined gemcitabine plus cisplatin and gemcitabine plus carboplatin chemotherapy in Chinese patients with a solitary kidney after nephroureterectomy
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-017-3316-7
Abstract: PurposeThe renal safety of cisplatin-based chemotherapy has not been investigated in patients with urothelial carcinoma of the upper urinary tract (UUT-UC) who retain a solitary kidney after nephroureterectomy. This study aimed to assess and compare… read more here.
Keywords: chemotherapy; renal safety; gemcitabine plus; solitary kidney ... See more keywords
Renal safety outcomes of spironolactone in patients with resistant hypertension
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DOI: 10.1016/j.nefroe.2020.08.001
Abstract: INTRODUCTION Resistant hypertension (RH) is a significant health problem with complex management. The aim of this study was to evaluate the risks and benefits of adding spironolactone to treat RH. MATERIAL AND METHODS In total,… read more here.
Keywords: safety outcomes; renal safety; resistant hypertension; hypertension ... See more keywords
EFFECTS OF CANAGLIFLOZIN ON CARDIOVASCULAR, RENAL AND SAFETY OUTCOMES BY BASELINE LOOP DIURETIC USE: DATA FROM THE CREDENCE TRIAL
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(20)32479-7
Abstract: Canagliflozin (CANA) reduces the risk of cardiovascular (CV) events and kidney failure in people with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD). Inherent in its mechanism of action is enhanced natriuresis and… read more here.
Keywords: canagliflozin cardiovascular; safety outcomes; renal safety; safety ... See more keywords
Renal safety of short‐term empiric gentamicin therapy in aged patients
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DOI: 10.1111/ajag.12541
Abstract: To determine the incidence of acute kidney injury (AKI) in aged patients receiving empiric gentamicin therapy. read more here.
Keywords: renal safety; gentamicin therapy; aged patients; empiric gentamicin ... See more keywords
P074 Significant efficacy and long term safety difference with taf-based str in naïve adults
Sign Up to like & getrecommendations! Published in 2017 at "Sexually Transmitted Infections"
DOI: 10.1136/sextrans-2017-053232.119
Abstract: Introduction At Week(W) 48, elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) was statistically noninferior to E/C/F/tenofovir disoproxil fumarate(TDF) for the proportion of subjects with HIV-1 RNA read more here.
Keywords: participants taf; p074 significant; renal safety; safety ... See more keywords
Comparison of renal safety of tenofovir and entecavir in patients with chronic hepatitis B: Systematic review with meta-analysis
Sign Up to like & getrecommendations! Published in 2019 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v25.i23.2961
Abstract: BACKGROUND Recently, the American Association for the Study of Liver Disease suggested no preference between tenofovir (TDF) and entecavir (ETV) regarding potential long-term risks of renal complications. Over the years, renal safety has become a… read more here.
Keywords: tenofovir entecavir; review meta; renal safety; systematic review ... See more keywords
Linagliptin: Cardiovascular and Renal Safety beyond Doubt at a Steep Price
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Pharmacology and Pharmacotherapeutics"
DOI: 10.4103/jpp.jpp_10_20
Abstract: Dipeptidyl peptidase-IV inhibitors or “gliptins” are commonly used oral anti-diabetic drugs for Type 2 diabetes mellitus, preferred as add-on therapy after metformin. Various cardiovascular outcome trials (CVOTs) have established their cardiovascular safety. Approved later than… read more here.
Keywords: safety beyond; price; renal safety; linagliptin cardiovascular ... See more keywords
Treatment Outcome and Renal Safety of 3-Year Tenofovir Disoproxil Fumarate Therapy in Chronic Hepatitis B Patients with Preserved Glomerular Filtration Rate
Sign Up to like & getrecommendations! Published in 2019 at "Gut and Liver"
DOI: 10.5009/gnl18183
Abstract: Background/Aims To investigate the treatment efficacy and renal safety of long-term tenofovir disoproxil fumarate (TDF) therapy in chronic hepatitis B (CHB) patients with preserved renal function. Methods The medical records of 919 CHB patients who… read more here.
Keywords: hepatitis; renal safety; treatment; patients preserved ... See more keywords