Impact of Chronic Sodium Fluoride Toxicity on Antioxidant Capacity, Biochemical Parameters, and Histomorphology in Cardiac, Hepatic, and Renal Tissues of Wistar Rats.
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DOI: 10.1007/s12011-022-03113-w
Abstract: The study was designed to determine the fluoride distribution after its oral exposure in drinking water and its associated impact on biochemical, antioxidant markers and histology in the liver, kidney, and heart of male Wistar… read more here.
Keywords: fluoride; wistar rats; exposure; heart ... See more keywords
TLR3 is involved in paraquat‐induced acute renal injury
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DOI: 10.1016/j.lfs.2019.03.029
Abstract: Aims To investigate the role of Toll‐like receptor 3 (TLR3) in mouse paraquat‐induced acute renal injury. Materials and methods Acute renal injury was established in C57BL/6J mice by intraperitoneal injection of paraquat (28 mg/kg). The… read more here.
Keywords: paraquat; renal tissues; acute renal; renal injury ... See more keywords
Depleted HDAC3 attenuates hyperuricemia-induced renal interstitial fibrosis via miR-19b-3p/SF3B3 axis
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DOI: 10.1080/15384101.2021.1989899
Abstract: ABSTRACT Dysfunctional histone deacetylases (HDACs) elicit unrestrained fibrosis and damage to organs. With regard to the link between HDACs and fibrosis, this research is practiced to decipher the concrete mechanism of HDAC3 in hyperuricemia (HN)-induced… read more here.
Keywords: 19b sf3b3; renal tissues; mir 19b; sf3b3 ... See more keywords
Profibrotic gene transcription in renal tissues from cats with ischemia-induced chronic kidney disease.
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DOI: 10.2460/ajvr.81.2.180
Abstract: OBJECTIVE To characterize transcription of profibrotic mediators in renal tissues of cats with ischemia-induced chronic kidney disease (CKD). SAMPLE Banked renal tissues from 6 cats with experimentally induced CKD (RI group) and 8 healthy control… read more here.
Keywords: transcription; renal tissues; mmp; tissues cats ... See more keywords
Tetramethylpyrazine alleviates acute kidney injury by inhibiting NLRP3/HIF-1α and apoptosis
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DOI: 10.3892/mmr.2020.11378
Abstract: The aim of the present study was to investigate the protective effect and underlying mechanism of tetramethylpyrazine (TMP) on renal ischemia reperfusion injury (RIRI) in rats, which refers to the injury caused by the restoration… read more here.
Keywords: renal tissues; group; tmp group; tetramethylpyrazine ... See more keywords