Development of Physiologically Based Pharmacokinetic Model and Assessment of the Impact of Renal Underdevelopment in Preterm Infants on the Pharmacokinetics of Aminophylline
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DOI: 10.1177/0976500x221080209
Abstract: Objective: To develop a physiologically based pharmacokinetic (PBPK) model for individualization of the dosing regimen considering the physiological requirements of these preterm neonates. Methods: The study comprised preterm newborns with fewer than 34 weeks of… read more here.
Keywords: pbpk model; renal underdevelopment; based pharmacokinetic; preterm ... See more keywords