Serum-soluble (pro)renin receptor concentration as a biomarker for organ damage in primary aldosteronism
Sign Up to like & getrecommendations! Published in 2019 at "Hypertension Research"
DOI: 10.1038/s41440-019-0312-9
Abstract: Primary aldosteronism is characterized by inappropriate overproduction of aldosterone by adrenal lesions and leads to hypertension. Excess aldosterone causes organ damage; therefore, finding a biomarker for organ damage risk is vital. The (pro)renin receptor regulates… read more here.
Keywords: renin; renin receptor; organ damage; pro renin ... See more keywords
The (pro)renin receptor: what’s in a name?
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Nephrology"
DOI: 10.1038/s41581-020-0274-9
Abstract: A. Ichihara and M. S. Yatabe (The (pro)renin receptor in health and disease. Nat. Rev. Nephrol. 15, 693–712 (2019))1. The (pro)renin receptor (PRR; also known as ATP6AP2) was first discovered in 1998 in a biochemical… read more here.
Keywords: medicine; renin; name; renin receptor ... See more keywords
Pro)renin Receptor RNA Interference Silencing Attenuates Diabetic Cardiomyopathy Pathological Process in Rats
Sign Up to like & getrecommendations! Published in 2019 at "Human Gene Therapy"
DOI: 10.1089/hum.2018.155
Abstract: (Pro)renin receptor (PRR) is a novel component of the renin–angiotensin system that has been demonstrated to be involved in cardiovascular diseases. Recent research reported that diabetic cardiomyo... read more here.
Keywords: pro renin; receptor rna; rna interference; interference silencing ... See more keywords
Revisiting the relationship between (Pro)Renin receptor and the intrarenal RAS: focus on the soluble receptor
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Nephrology and Hypertension"
DOI: 10.1097/mnh.0000000000000806
Abstract: Purpose of review The (pro)renin receptor (PRR), also termed as ATPase H+ transporting accessory protein 2 (ATP6AP2), was originally cloned as a specific receptor for prorenin and renin [together called (pro)renin]. Given the wide tissue… read more here.
Keywords: renin receptor; prr; renin; receptor ... See more keywords
Neuronal (pro)renin receptor regulates deoxycorticosterone-induced sodium intake.
Sign Up to like & getrecommendations! Published in 2018 at "Physiological genomics"
DOI: 10.1152/physiolgenomics.00065.2018
Abstract: Increased sodium appetite is a physiological response to sodium deficiency; however, it has also been implicated in disease conditions such as congestive heart failure, kidney failure, and salt-sensitive hypertension. The central nervous system is the… read more here.
Keywords: sodium intake; sodium; renin receptor; pro renin ... See more keywords
Soluble (pro)renin receptor level in patients with severe obesity is associated with visceral adiposity and is involved with insulin resistance and renal injury.
Sign Up to like & getrecommendations! Published in 2023 at "Obesity facts"
DOI: 10.1159/000531076
Abstract: INTRODUCTION High soluble (pro)renin receptor (s(P)RR) level in circulation is reported in obese patients; however, it is unclear which body composition components are responsible for it. In this study, the authors examined blood s(P)RR levels… read more here.
Keywords: soluble pro; renin receptor; receptor level; level ... See more keywords
Serum soluble (pro)renin receptor level as a prognostic factor in patients undergoing maintenance hemodialysis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the Endocrine Society"
DOI: 10.21203/rs.3.rs-379462/v1
Abstract: The (pro)renin receptor [(P)RR)] is a multifunctional protein that is cleaved to generate the soluble (P)RR [s(P)RR], reflecting the status of the tissue renin-angiotensin system and/or activity of the (P)RR. The serum s(P)RR level is… read more here.
Keywords: serum; pro renin; level; patients undergoing ... See more keywords
The role of (pro)renin receptor and its soluble form in cardiovascular diseases
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2023.1086603
Abstract: The renin-angiotensin system (RAS) is a major classic therapeutic target for cardiovascular diseases. In addition to the circulating RAS, local tissue RAS has been identified in various tissues and plays roles in tissue inflammation and… read more here.
Keywords: soluble form; cardiovascular diseases; renin receptor; pro renin ... See more keywords
(Pro)renin Receptor Regulates Phosphate Homeostasis in Rats via Releasing Fibroblast Growth Factor-23
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.784521
Abstract: Phosphate (Pi) is one of the basic necessities required for sustenance of life and its metabolism largely relies on excretory function of the kidney, a process chiefly under the endocrine control of bone-derived fibroblast growth… read more here.
Keywords: pro renin; fibroblast growth; growth factor; renin receptor ... See more keywords
Soluble (Pro)Renin Receptor Levels Are Regulated by Plasma Renin Activity and Correlated with Edema in Mice and Humans with HFrEF
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10081874
Abstract: Symptomatic heart failure with reduced ejection fraction (HFrEF) is characterized by edema and chronic pathological activation of the classical renin–angiotensin–aldosterone system (RAAS). The soluble (pro)renin receptor (s(P)RR) is released into circulation by proteolytic cleavage of… read more here.
Keywords: soluble pro; renin receptor; dysfunction; renin ... See more keywords
(Pro)renin Receptor Expression Increases throughout the Colorectal Adenoma—Adenocarcinoma Sequence and It Is Associated with Worse Colorectal Cancer Prognosis
Sign Up to like & getrecommendations! Published in 2019 at "Cancers"
DOI: 10.3390/cancers11060881
Abstract: (Pro)renin receptor (PRR) is a protein that takes part in several signaling pathways such as Renin Angiotensin System and Wnt signalling. Its biological role has recently been related to cancer progression and in this study,… read more here.
Keywords: colorectal cancer; renin receptor; expression; pro renin ... See more keywords