Diabetic nephropathy: Renoprotective effects of GLP1R agonists and SGLT2 inhibitors
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DOI: 10.1038/nrneph.2017.140
Abstract: New data from the LEADER trial show that the glucagon-like peptide 1 receptor agonist liraglutide protects against diabetic nephropathy in patients with type 2 diabetes mellitus. The renoprotective efficacy of liraglutide is not, however, as… read more here.
Keywords: nephropathy renoprotective; renoprotective effects; glp1r agonists; effects glp1r ... See more keywords
Renoprotective effects of dulaglutide in patients with T2DM and CKD
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Nephrology"
DOI: 10.1038/s41581-018-0055-x
Abstract: The AWARD-7 trial shows that the glucagon-like peptide 1 (GLP1) receptor agonist dulaglutide, which is not cleared by the kidney, seems to be renoprotective, ameliorates albuminuria and slows estimated glomerular filtration rate decline in patients… read more here.
Keywords: effects dulaglutide; renoprotective effects; t2dm ckd; patients t2dm ... See more keywords
New Glucose-Lowering Agents for Diabetic Kidney Disease.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in chronic kidney disease"
DOI: 10.1053/j.ackd.2018.01.002
Abstract: The prevalence of diabetes mellitus is increasing and is associated with a range of complications including nephropathy. New antidiabetic agents are sought which also have positive effects to diminish diabetic complications. Examples of promising new… read more here.
Keywords: renoprotective effects; disease new; new glucose; kidney disease ... See more keywords
Renoprotective effects of topiroxostat for Hyperuricaemic patients with overt diabetic nephropathy study (ETUDE study): A prospective, randomized, multicentre clinical trial
Sign Up to like & getrecommendations! Published in 2018 at "Nephrology"
DOI: 10.1111/nep.13177
Abstract: We aimed to evaluate the anti‐albuminuric effects of topiroxostat in Japanese hyperuricaemic patients with diabetic nephropathy. read more here.
Keywords: effects topiroxostat; study; renoprotective effects; topiroxostat hyperuricaemic ... See more keywords
Corrigendum to “Renoprotective Effects of Aldose Reductase Inhibitor Epalrestat against High Glucose-Induced Cellular Injury”
Sign Up to like & getrecommendations! Published in 2019 at "BioMed Research International"
DOI: 10.1155/2019/9406241
Abstract: [This corrects the article DOI: 10.1155/2017/5903105.]. read more here.
Keywords: reductase inhibitor; aldose reductase; effects aldose; renoprotective effects ... See more keywords
Prolonged Duration of Erythropoiesis-Stimulating Agents' Action Delays Disease Progression in Anti-Thy 1 Antibody-Induced Chronic Glomerulonephritis Rats.
Sign Up to like & getrecommendations! Published in 2020 at "Pharmacology"
DOI: 10.1159/000506995
Abstract: BACKGROUND Although erythropoiesis-stimulating agents (ESAs) exert renoprotective effects in renal disease models, it has not been revealed whether the prolonged duration of action of ESAs contributes to their renoprotective effects. OBJECTIVE We examined whether the… read more here.
Keywords: prolonged duration; erythropoiesis stimulating; duration; disease ... See more keywords
Abstract P2044: Renoprotective Effects of Canagliflozin in Db/db Diabetic Mice
Sign Up to like & getrecommendations! Published in 2019 at "Hypertension"
DOI: 10.1161/hyp.74.suppl_1.p2044
Abstract: Diabetes is one of the major causes of chronic kidney disease which could lead to end-stage renal disease. Previously, we have shown increased urinary angiotensin converting enzyme 2 (ACE2) and neprilysin (NEP) in db/db mouse… read more here.
Keywords: effects canagliflozin; renoprotective effects; expression; mice ... See more keywords
A Review of the Renoprotective Effects of Novel Antidiabetic Agents
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DOI: 10.1177/0897190020902344
Abstract: The objective of this review article was to identify and examine current evidence surrounding the potential renoprotective effects of newer antidiabetic agents such as sodium-glucose cotransporter 2 (SGLT-2) inhibitors, glucose-like peptide 1 (GLP-1) agonists, and… read more here.
Keywords: review renoprotective; sglt inhibitors; renoprotective effects; inhibitors glp ... See more keywords
Antihypertensive, antidyslipidemic, and renoprotective effects of Bursera simaruba on metabolic syndrome
Sign Up to like & getrecommendations! Published in 2023 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2023.66530.14601
Abstract: Objective(s): Metabolic syndrome is associated with the development of chronic kidney disease. Bursera simaruba “chaca” is a medicinal plant used in Mexico for hypertension and empirical therapy. In this study, were examined the effects of… read more here.
Keywords: metabolic syndrome; simaruba metabolic; bursera simaruba; syndrome ... See more keywords