Preparation, Characterization and Crystal Structures of a Key Intermediate, and a Significant Impurity, in the Synthesis of Repaglinide
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Chemical Crystallography"
DOI: 10.1007/s10870-019-00811-7
Abstract: Abstract The crystal structure of 2-(3-ethoxy-4-(methoxycarbonyl)phenyl) acetic acid ( RGA ), an important intermediate in the preparation of Repaglinide, has been carried out. Hydrogen bonds between the carboxylate groups link the molecules into dimers while… read more here.
Keywords: key intermediate; crystal structures; impurity; preparation characterization ... See more keywords
A time to revisit the two oldest prandial anti-diabetes agents: acarbose and repaglinide
Sign Up to like & getrecommendations! Published in 2020 at "Endocrine"
DOI: 10.1007/s12020-020-02396-0
Abstract: Purpose Compared with newer prandial anti-diabetes agents, repaglinide and acarbose are unique in being globally available in generic versions, being oral, and being the cheapest of all. The aim of this study was to compare… read more here.
Keywords: diabetes agents; prandial anti; group; acarbose repaglinide ... See more keywords
A new rapid and economic liquid chromatographic method for simultaneous determination of meglitinides with metformin: application in the presence of metformin and repaglinide impurities and related compounds
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Iranian Chemical Society"
DOI: 10.1007/s13738-017-1209-7
Abstract: A new liquid chromatographic method was developed for simultaneous determination of the widely used oral antidiabetic, metformin hydrochloride with antidiabetics comprising the meglitinides class in bulk, laboratory-prepared mixtures and pharmaceutical products. It was applied in… read more here.
Keywords: presence; determination; metformin; method ... See more keywords