Using Registry Data to Fill Blind Spots From Randomized Trials of Abdominal Aortic Aneurysm Repair.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2022.12092
Abstract: The study by Yei and coauthors 1 describes 6-year results of abdominal aortic aneurysm (AAA) repair performed via open aneurysm repair (OAR) vs endovascular aneurysm repair (EVAR) using the Vascular Quality Initiative (VQI) Vascular Implant… read more here.
Keywords: aneurysm repair; abdominal aortic; registry; aortic aneurysm ... See more keywords
Patient-Proxy and Societal Perspectives of Quality-of-Life Utilities in Children With Cleft Lip and Palate Managed With Surgical Repair vs No Repair in Ethiopia
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.20900
Abstract: This cross-sectional study examines patient-proxy and societal perspectives of quality-of-life utilities for untreated and surgically treated children with cleft lip and palate. read more here.
Keywords: perspectives quality; societal perspectives; patient proxy; proxy societal ... See more keywords
Recurrence Rates After Repair of Inguinal Hernia in Women: A Systematic Review
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Surgery"
DOI: 10.1001/jamasurg.2018.3102
Abstract: Importance To our knowledge, a systematic review has not yet been performed that specifically addresses the management of inguinal hernia in women. Recurrence after repair of inguinal hernia is not unusual in women and may… read more here.
Keywords: hernia; recurrence rates; inguinal hernia; hernia women ... See more keywords
Annexins A1 and A2 are recruited to larger lysosomal injuries independently of ESCRTs to promote repair
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14329
Abstract: Damaged lysosomes can be repaired by calcium release‐dependent recruitment of the ESCRT machinery. However, the involvement of annexins, another group of calcium‐responding membrane repair proteins, has not been fully addressed. Here, we show that although… read more here.
Keywords: larger lysosomal; recruited larger; annexins recruited; anxa1 anxa2 ... See more keywords
Exploiting DNA repair defects in colorectal cancer
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12467
Abstract: Colorectal cancer (CRC) is the third leading cause of cancer‐related deaths worldwide. Therapies that take advantage of defects in DNA repair pathways have been explored in the context of breast, ovarian, and other tumor types,… read more here.
Keywords: dna repair; colorectal cancer; repair defects; exploiting dna ... See more keywords
Resistance to DNA repair inhibitors in cancer
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13224
Abstract: The DNA damage response (DDR) represents a complex network of proteins which detect and repair DNA damage, thereby maintaining the integrity of the genome and preventing the transmission of mutations and rearranged chromosomes to daughter… read more here.
Keywords: resistance; ddr; cancer; resistance dna ... See more keywords
DNA repair as a shared hallmark in cancer and ageing
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DOI: 10.1002/1878-0261.13285
Abstract: Increasing evidence demonstrates that DNA damage and genome instability play a crucial role in ageing. Mammalian cells have developed a wide range of complex and well‐orchestrated DNA repair pathways to respond to and resolve many… read more here.
Keywords: dna repair; shared hallmark; repair shared; cancer ... See more keywords
ARL2 is required for homologous recombination repair and colon cancer stem cell survival
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13438
Abstract: ARL2 regulates the dynamics of cytological components and is highly expressed in colon cancer tissues. Here, we report novel roles of ARL2 in the cell nucleus and colon cancer stem cells (CSCs). ARL2 is expressed… read more here.
Keywords: arl2; cancer stem; colon cancer; colon ... See more keywords
Nanofibrillar Decellularized Wharton's Jelly Matrix for Segmental Tracheal Repair
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Functional Materials"
DOI: 10.1002/adfm.201910067
Abstract: Wharton's jelly (WJ) is considered a potential scaffold in tissue‐engineered trachea for its similar composition and function to cartilage tissue. However, the feasibility of using WJ to construct engineered neocartilage tissue has not been reported,… read more here.
Keywords: tissue; tracheal; repair; wharton jelly ... See more keywords
Tropoelastin Implants That Accelerate Wound Repair
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201701206
Abstract: A novel, pure, synthetic material is presented that promotes the repair of full-thickness skin wounds. The active component is tropoelastin and leverages its ability to promote new blood vessel formation and its cell recruiting properties… read more here.
Keywords: accelerate wound; wound repair; tropoelastin implants; implants accelerate ... See more keywords
A Bioprinted Cardiac Patch Composed of Cardiac‐Specific Extracellular Matrix and Progenitor Cells for Heart Repair
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DOI: 10.1002/adhm.201800672
Abstract: Congenital heart defects are present in 8 of 1000 newborns and palliative surgical therapy has increased survival. Despite improved outcomes, many children develop reduced cardiac function and heart failure requiring transplantation. Human cardiac progenitor cell… read more here.
Keywords: heart; extracellular matrix; progenitor; cecm ... See more keywords