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   Articles with "repair" as a keyword



Using Registry Data to Fill Blind Spots From Randomized Trials of Abdominal Aortic Aneurysm Repair.

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recommendations! Published in 2022 at "JAMA network open"

DOI: 10.1001/jamanetworkopen.2022.12092

Abstract: The study by Yei and coauthors 1 describes 6-year results of abdominal aortic aneurysm (AAA) repair performed via open aneurysm repair (OAR) vs endovascular aneurysm repair (EVAR) using the Vascular Quality Initiative (VQI) Vascular Implant… read more here.

Keywords: aneurysm repair; abdominal aortic; registry; aortic aneurysm ... See more keywords

Patient-Proxy and Societal Perspectives of Quality-of-Life Utilities in Children With Cleft Lip and Palate Managed With Surgical Repair vs No Repair in Ethiopia

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recommendations! Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2022.20900

Abstract: This cross-sectional study examines patient-proxy and societal perspectives of quality-of-life utilities for untreated and surgically treated children with cleft lip and palate. read more here.

Keywords: perspectives quality; societal perspectives; patient proxy; proxy societal ... See more keywords

Trends in the Management of Anterior Mitral Leaflet Regurgitation

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recommendations! Published in 2024 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2024.6726

Abstract: Key Points Question What is the prevalence and trend of isolated anterior leaflet mitral valve (MV) repair and replacement (MVR) over the past decade in the US? Findings In this cross-sectional study that included 16 259… read more here.

Keywords: mitral leaflet; regurgitation; repair; management anterior ... See more keywords

Recurrence Rates After Repair of Inguinal Hernia in Women: A Systematic Review

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recommendations! Published in 2018 at "JAMA Surgery"

DOI: 10.1001/jamasurg.2018.3102

Abstract: Importance To our knowledge, a systematic review has not yet been performed that specifically addresses the management of inguinal hernia in women. Recurrence after repair of inguinal hernia is not unusual in women and may… read more here.

Keywords: hernia; recurrence rates; inguinal hernia; hernia women ... See more keywords

Surgical Approach and Long-Term Recurrence After Ventral Hernia Repair

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recommendations! Published in 2024 at "JAMA Surgery"

DOI: 10.1001/jamasurg.2024.1696

Abstract: Key Points Question How do long-term operative recurrence rates for anterior abdominal wall (ventral) hernia compare after robotic-assisted, laparoscopic, and open hernia repairs? Findings This cohort study of Medicare claims data identified 161 415 patients who… read more here.

Keywords: hernia repair; long term; repair; hernia ... See more keywords

Use of Biologic and Biosynthetic Mesh for Ventral Hernia Repair in Current Practice.

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recommendations! Published in 2024 at "JAMA surgery"

DOI: 10.1001/jamasurg.2024.5293

Abstract: Importance Originally developed for use in contaminated fields, there is growing evidence against the use of biologic and biosynthetic mesh in ventral hernia repair. However, its prevalence and patterns of use in current practice are… read more here.

Keywords: biosynthetic mesh; use; repair; hernia ... See more keywords

Annexins A1 and A2 are recruited to larger lysosomal injuries independently of ESCRTs to promote repair

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recommendations! Published in 2022 at "FEBS Letters"

DOI: 10.1002/1873-3468.14329

Abstract: Damaged lysosomes can be repaired by calcium release‐dependent recruitment of the ESCRT machinery. However, the involvement of annexins, another group of calcium‐responding membrane repair proteins, has not been fully addressed. Here, we show that although… read more here.

Keywords: larger lysosomal; recruited larger; annexins recruited; anxa1 anxa2 ... See more keywords

Traffic light at DSB–transit regulation between gene transcription and DNA repair

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recommendations! Published in 2024 at "Febs Letters"

DOI: 10.1002/1873-3468.15024

Abstract: Transcription of actively expressed genes is dampened for kilobases around DNA lesions via chromatin modifications. This is believed to favour repair and prevent genome instability. Nonetheless, mounting evidence suggests that transcription may be induced by… read more here.

Keywords: traffic light; repair; dna repair; light dsb ... See more keywords

The role of histone modifications in transcription regulation upon DNA damage.

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recommendations! Published in 2025 at "FEBS letters"

DOI: 10.1002/1873-3468.70241

Abstract: Cells are constantly exposed to various sources of DNA damage, including radiation, chemicals, replicative stress and oxidative stress, that threaten genome stability. To ensure faithful DNA repair, transcription regulation needs to be tightly controlled. This… read more here.

Keywords: dna damage; repair; regulation; transcription ... See more keywords
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Exploiting DNA repair defects in colorectal cancer

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recommendations! Published in 2019 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12467

Abstract: Colorectal cancer (CRC) is the third leading cause of cancer‐related deaths worldwide. Therapies that take advantage of defects in DNA repair pathways have been explored in the context of breast, ovarian, and other tumor types,… read more here.

Keywords: dna repair; colorectal cancer; repair defects; exploiting dna ... See more keywords

Resistance to DNA repair inhibitors in cancer

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recommendations! Published in 2022 at "Molecular Oncology"

DOI: 10.1002/1878-0261.13224

Abstract: The DNA damage response (DDR) represents a complex network of proteins which detect and repair DNA damage, thereby maintaining the integrity of the genome and preventing the transmission of mutations and rearranged chromosomes to daughter… read more here.

Keywords: resistance; ddr; cancer; resistance dna ... See more keywords