Germline and somatic DNA repair gene alterations in prostate cancer
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DOI: 10.1002/cncr.32908
Abstract: Emerging evidence has suggested that DNA repair gene alterations may be important in prostate cancer pathogenesis. In the current study, the authors sought to characterize alterations in DNA repair pathway genes in both primary and… read more here.
Keywords: dna repair; gene alterations; prostate cancer; repair gene ... See more keywords
Rapid Screen of Potential i-Motif Forming Sequences in DNA Repair Gene Promoters
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DOI: 10.1021/acsomega.8b01551
Abstract: We have studied the in vitro stability of 25 potential i-motif-forming DNA sequences found within the promoter regions of 18 different human DNA repair genes. Three widely available methods of characterization were used to rapidly… read more here.
Keywords: motif; potential motif; motif forming; dna repair ... See more keywords
The value of diffusion kurtosis imaging in assessing mismatch repair gene expression of rectal carcinoma: Preliminary findings
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DOI: 10.1371/journal.pone.0211461
Abstract: Purpose To determine the correlation between the parameters of MR diffusion kurtosis imaging (MR-DKI) and mismatch repair gene expression (MMR) for rectal carcinomas. Materials and methods Data from 80 patients with rectal carcinoma were analyzed… read more here.
Keywords: repair gene; expression; kurtosis; kurtosis imaging ... See more keywords
DNA Repair Gene Polymorphisms and Chromosomal Aberrations in Exposed Populations
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DOI: 10.3389/fgene.2021.691947
Abstract: DNA damage and unrepaired or insufficiently repaired DNA double-strand breaks as well as telomere shortening contribute to the formation of structural chromosomal aberrations (CAs). Non-specific CAs have been used in the monitoring of individuals exposed… read more here.
Keywords: dna repair; chromosomal aberrations; gene polymorphisms; repair gene ... See more keywords
A Combined Epithelial Mesenchymal Transformation and DNA Repair Gene Panel in Colorectal Cancer With Prognostic and Therapeutic Implication
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DOI: 10.3389/fonc.2020.595182
Abstract: Background Epithelial mesenchymal transformation (EMT) and DNA repair status represent intrinsic features of colorectal cancer (CRC) and are associated with patient prognosis and treatment responsiveness. We sought to develop a combined EMT and DNA repair… read more here.
Keywords: dna repair; repair gene; emt dna; gene panel ... See more keywords