Facile preparation of model DNA interstrand cross-link repair intermediates using ribonucleotide-containing DNA.
Sign Up to like & getrecommendations! Published in 2022 at "DNA repair"
DOI: 10.1016/j.dnarep.2022.103286
Abstract: DNA interstrand cross-links (ICLs) are lesions with a covalent bond formed between DNA strands. ICLs are extremely toxic to cells because they prevent the separation of the two strands, which are necessary for the genetic… read more here.
Keywords: dna; dna interstrand; repair; repair intermediates ... See more keywords
DNA Base Excision Repair Intermediates Influence Duplex–Quadruplex Equilibrium
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28030970
Abstract: Although genomic DNA is predominantly duplex under physiological conditions, particular sequence motifs can favor the formation of alternative secondary structures, including the G-quadruplex. These structures can exist within gene promoters, telomeric DNA, and regions of… read more here.
Keywords: dna; duplex quadruplex; damage; repair intermediates ... See more keywords