Ablating putative Ku70 phosphorylation sites results in defective DNA damage repair and spontaneous induction of hepatocellular carcinoma
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DOI: 10.1093/nar/gkab743
Abstract: Abstract Multiple pathways mediate the repair of DNA double-strand breaks (DSBs), with numerous mechanisms responsible for driving choice between the pathways. Previously, we reported that mutating five putative phosphorylation sites on the non-homologous end joining… read more here.
Keywords: hepatocellular carcinoma; repair spontaneous; ku70; phosphorylation sites ... See more keywords