NEIL3 Repairs Telomere Damage during S Phase to Secure Chromosome Segregation at Mitosis.
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DOI: 10.1016/j.celrep.2017.08.020
Abstract: Oxidative damage to telomere DNA compromises telomere integrity. We recently reported that the DNA glycosylase NEIL3 preferentially repairs oxidative lesions in telomere sequences in vitro. Here, we show that loss of NEIL3 causes anaphase DNA bridging because… read more here.
Keywords: damage phase; repairs telomere; neil3 repairs; phase secure ... See more keywords