The leucine-rich repeat domain of human peroxidasin 1 promotes binding to laminin in basement membranes.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2020.108443
Abstract: Human peroxidasin 1 (PXDN) is a homotrimeric multidomain heme peroxidase and essential for tissue development and architecture. It has a biosynthetic function and catalyses the hypobromous acid-mediated formation of specific covalent sulfilimine (SN) bonds, which… read more here.
Keywords: leucine rich; repeat domain; human peroxidasin; basement membranes ... See more keywords
WD Repeat Domain 1 (WDR1) Deficiency Presenting as a Cause of Infantile Inflammatory Bowel Disease
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Pediatric Gastroenterology and Nutrition"
DOI: 10.1097/mpg.0000000000002826
Abstract: Supplemental Digital Content is available in the text ABSTRACT Infantile and very early onset inflammatory bowel disease (VEOIBD) are a rare phenomenon wherein patients develop intestinal inflammation with typical IBD symptoms before ages 2 and… read more here.
Keywords: domain wdr1; bowel disease; repeat domain; inflammatory bowel ... See more keywords
GLCCI1 reduces collagen deposition and airway hyper‐responsiveness in a mouse asthma model through binding with WD repeat domain 45B
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.16658
Abstract: Asthma is a serious public health problem worldwide, without effective therapeutic methods. Our previous study indicated that glucocorticoid‐induced transcript 1 gene (GLCCI1) knockout reduces the sensitivity to glucocorticoid in asthmatic mouse. Here, we explored the… read more here.
Keywords: domain 45b; glcci1 reduces; repeat domain; glcci1 ... See more keywords
WD Repeat Domain 77 Protein Regulates Translation of E2F1 and E2F3 mRNA
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00302-20
Abstract: WD repeat domain 77 protein (WDR77) is required for cellular proliferation of lung and prostate epithelial cells during earlier stages of development and is reactivated during prostate and lung tumorigenesis. WDR77 plays an essential role… read more here.
Keywords: wdr77; e2f1 e2f3; translation; e2f3 ... See more keywords
Functional domain studies uncover novel roles for the ZTL Kelch repeat domain in clock function
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DOI: 10.1371/journal.pone.0235938
Abstract: The small LOV/F-box/Kelch family of E3 ubiquitin ligases plays an essential role in the regulation of plant circadian clocks and flowering time by sensing dusk. The family consists of three members, ZEITLUPE (ZTL), LOV KELCH… read more here.
Keywords: ztl kelch; kelch repeat; domain; repeat domain ... See more keywords
Tetratricopeptide repeat domain 9A knockout induces social anxiety and impairs offense behaviors in female mice
Sign Up to like & getrecommendations! Published in 2022 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2022.63044.13932
Abstract: Objective(s): The involvement of tetratricopeptide repeat domain 9A (TTC9A) in anxiety-like behaviors through estrogen action has been reported in female mice, this study further investigated its effects on social anxiety and aggressive behaviors. Materials and… read more here.
Keywords: female mice; tetratricopeptide repeat; repeat domain; social anxiety ... See more keywords
A Pan-Cancer Analysis of the Oncogenic Role of WD Repeat Domain 74 in Multiple Tumors
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.860940
Abstract: Although emerging patient-derived samples and cellular-based evidence support the relationship between WDR74 (WD Repeat Domain 74) and carcinogenesis in multiple cancers, no systematic pan-cancer analysis is available. Our preliminary research demonstrated that WDR74 is over-expressed… read more here.
Keywords: repeat domain; pan cancer; analysis; cancer analysis ... See more keywords
Prognostic role of ring finger and WD repeat domain 3 and immune cell infiltration in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "World Journal of Hepatology"
DOI: 10.4254/wjh.v15.i1.116
Abstract: We have found that the expression of ring finger and WD repeat domain 3 (RFWD3) is significantly higher in unpaired and paired hepatocellular carcinoma (HCC) tissues than in normal tissues. Moreover, this expression has a… read more here.
Keywords: hepatocellular carcinoma; ring finger; repeat domain; immune cell ... See more keywords