Use of second doses of Valtoco® (diazepam nasal spray) across 24 hours after the initial dose for out‐of‐hospital seizure clusters: Results from a phase 3, open‐label, repeat‐dose safety study
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DOI: 10.1111/epi.17177
Abstract: An exploratory analysis from a long‐term, phase 3, open‐label, repeat‐dose safety study of diazepam nasal spray for acute treatment of seizure clusters assessed the use of a second dose up to 24 hours after the… read more here.
Keywords: repeat dose; dose safety; phase open; safety study ... See more keywords
Does the repeat dose of gonadotropin-releasing hormone agonist trigger in polycystic ovarian syndrome improve in vitro fertilization cycles outcome? A clinical trial study
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DOI: 10.18502/ijrm.v13i7.7363
Abstract: Abstract Background A repeat dose of Gonadotropin-releasing Hormone (GnRH) agonist could provide long duration of luteinizing hormone (LH) surge and amplitude appropriately. Objective Improvement in oocyte maturity could be obtained by a repeat dose of… read more here.
Keywords: agonist; study; repeat dose; maturity ... See more keywords
The Effects of Repeat-Dose Doxorubicin on Cardiovascular Functional Endpoints and Biomarkers in the Telemetry-Equipped Cynomolgus Monkey
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DOI: 10.3389/fcvm.2021.587149
Abstract: Purpose: Doxorubicin-related heart failure has been recognized as a serious complication of cancer chemotherapy. This paper describes a cardiovascular safety pharmacology study with chronic dosing of doxorubicin in a non-human primate model designed to characterize… read more here.
Keywords: repeat dose; study; cynomolgus monkey; doxorubicin ... See more keywords