Global analysis of inverted repeat sequences in human gene promoters reveals their non-random distribution and association with specific biological pathways.
Sign Up to like & getrecommendations! Published in 2020 at "Genomics"
DOI: 10.1016/j.ygeno.2020.03.014
Abstract: Inverted repeats (IR) play important roles in specific DNA-dependent processes in simple prokaryotes to complex eukaryotes. They are recognized by a variety of proteins including restriction enzymes, helicases and transcription factors. We evaluate the presence… read more here.
Keywords: repeat sequences; biological pathways; global analysis; inverted repeat ... See more keywords
Accelerated Simulations Reveal Physicochemical Factors Governing Stability and Composition of RNA Clusters
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DOI: 10.1021/acs.jctc.4c00803
Abstract: Under certain conditions, RNA repeat sequences phase separate, yielding protein-free biomolecular condensates. Importantly, RNA repeat sequences have also been implicated in neurological disorders, such as Huntington’s disease. Thus, mapping repeat sequences to their phase behavior,… read more here.
Keywords: rna; repeat sequences; stability composition;
Chronological set of E. coli O157:H7 bovine strains establishes a role for repeat sequences and mobile genetic elements in genome diversification
Sign Up to like & getrecommendations! Published in 2020 at "BMC Genomics"
DOI: 10.1186/s12864-020-06943-x
Abstract: Enterohemorrhagic Escherichia coli O157:H7 (EHEC) is a significant foodborne pathogen that resides asymptomatically within cattle and other ruminants. The EHEC genome harbors an extensive collection of mobile genetic elements (MGE), including multiple prophage, prophage-like elements,… read more here.
Keywords: repeat sequences; farm; repeat; prophage ... See more keywords
Synthesis and cloning of long repeat sequences using single-stranded circular DNA
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2023.1115159
Abstract: Non-coding repeat expansion causes several neurodegenerative diseases, such as fragile X syndrome, amyotrophic lateral sclerosis/frontotemporal dementia, and spinocerebellar ataxia (SCA31). Such repetitive sequences must be investigated to understand disease mechanisms and prevent them, using novel… read more here.
Keywords: single stranded; long repeat; repeat; sequences using ... See more keywords
Comparative Chloroplast Genomics of Seven Endangered Cypripedium Species and Phylogenetic Relationships of Orchidaceae
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DOI: 10.3389/fpls.2022.911702
Abstract: The species in the genus Cypripedium (Orchidaceae) are considered endangered, mainly distributed in the temperate regions of the Northern Hemisphere, with high ornamental and economic value. Despite previous extensive studies based on both morphology and… read more here.
Keywords: chloroplast; cypripedium; repeat sequences; chloroplast genomics ... See more keywords
Interaction of Proteins with Inverted Repeats and Cruciform Structures in Nucleic Acids
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23116171
Abstract: Cruciforms occur when inverted repeat sequences in double-stranded DNA adopt intra-strand hairpins on opposing strands. Biophysical and molecular studies of these structures confirm their characterization as four-way junctions and have demonstrated that several factors influence… read more here.
Keywords: inverted repeat; dna; inverted repeats; repeat sequences ... See more keywords