Bone Generation Following Repeated Administration of Recombinant Bone Morphogenetic Protein 2
Sign Up to like & getrecommendations! Published in 2020 at "Tissue Engineering and Regenerative Medicine"
DOI: 10.1007/s13770-020-00290-4
Abstract: Background: The delivery of recombinant human bone morphogenetic protein 2 (rhBMP2) by using various carriers has been used to successfully induce bone formation in many animal models. However, the effect of multiple administration of rhBMP2… read more here.
Keywords: administration; administration rhbmp2; repeated administration; bone ... See more keywords
Effect of single and repeated administration of amitriptyline on neuropathic pain model in rats: Focus on glutamatergic and upstream nitrergic systems.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.116752
Abstract: AIMS Few studies have compared the interaction of single and repeated administration of amitriptyline (amit) with the nitrergic system and glutamatergic system in the experimental model of neuropathic pain. We aimed to evaluate the antinociceptive… read more here.
Keywords: administration; single repeated; repeated administration; effect single ... See more keywords
Inhibition of catechol-O-methyltransferase in the cynomolgus monkey by opicapone after acute and repeated administration
Sign Up to like & getrecommendations! Published in 2018 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2018.10.001
Abstract: Introduction: The aim of the study was to clarify the dose response for inhibition of catechol‐O‐methyltransferase (COMT) by opicapone, a third generation COMT inhibitor, after acute and repeated administration to the cynomolgus monkey with pharmacokinetic… read more here.
Keywords: opicapone; inhibition; comt inhibition; repeated administration ... See more keywords
Toxicological evaluation of repeated administration of povidone iodine in cockerels
Sign Up to like & getrecommendations! Published in 2022 at "Toxicology Reports"
DOI: 10.1016/j.toxrep.2022.02.010
Abstract: Povidone-iodine (Polidine®) is a synthetic broad-spectrum antiseptic being applied topically to treat wounds and prevent their infection. It has been however reported with the assertions that it is effective in the treatment of infectious bursa… read more here.
Keywords: povidone; evaluation repeated; toxicological evaluation; povidone iodine ... See more keywords
Repeated administration of the NSAID meloxicam alters the plasma and urine lipidome
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-40686-4
Abstract: Non-steroidal anti-inflammatories (NSAIDs), such as meloxicam, are the mainstay for treating painful and inflammatory conditions in animals and humans; however, the repeated administration of NSAIDs can cause adverse effects, limiting the long-term administration of these… read more here.
Keywords: administration; plasma urine; repeated administration; urine lipidome ... See more keywords
Repeated Administration Effects on Psychomotor Vigilance Test Performance
Sign Up to like & getrecommendations! Published in 2018 at "SLEEP"
DOI: 10.1093/sleep/zsx187
Abstract: Study Objectives The Psychomotor Vigilance Test (PVT) is reported to be free of practice effects that can otherwise confound the effects of sleep loss and circadian misalignment on performance. This differentiates the PVT from more… read more here.
Keywords: pvt; administration; repeated administration; performance ... See more keywords
The Repeated Administration of Resveratrol Has Measurable Effects on Circulating T-Cell Subsets in Humans
Sign Up to like & getrecommendations! Published in 2017 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2017/6781872
Abstract: Preclinical studies have shown that resveratrol exerts immunomodulatory effects with potential clinical value in the amelioration of autoimmune disorders and cancer prevention; however, little is known about the in vivo effects of this naturally occurring… read more here.
Keywords: resveratrol; resveratrol measurable; repeated administration; administration resveratrol ... See more keywords
Is Forced Swimming Immobility a Good Endpoint for Modeling Negative Symptoms of Schizophrenia? - Study of Sub-Anesthetic Ketamine Repeated Administration Effects.
Sign Up to like & getrecommendations! Published in 2017 at "Anais da Academia Brasileira de Ciencias"
DOI: 10.1590/0001-3765201720160844
Abstract: Immobility time in the forced swimming has been described as analogous to emotional blunting or apathy and has been used for characterizing schizophrenia animal models. Several clinical studies support the use of NMDA receptor antagonists… read more here.
Keywords: immobility; schizophrenia; repeated administration; forced swimming ... See more keywords
Repeated administration of mazindol reduces spontaneous pain-related behaviors without modifying bone density and microarchitecture in a mouse model of complete Freund’s adjuvant-induced knee arthritis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pain Research"
DOI: 10.2147/jpr.s136581
Abstract: Background The role of dopaminergic system in the development of rheumatoid arthritis-related pain, a major symptom in this disease, has not been explored. Therefore, the anti-nociceptive effect of mazindol, a dopamine uptake inhibitor, was evaluated… read more here.
Keywords: administration; repeated administration; mazindol; bone ... See more keywords
Repeated Administration of Cigarette Smoke Condensate Increases Glutamate Levels and Behavioral Sensitization
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2018.00047
Abstract: Nicotine, a nicotinic acetylcholine receptor agonist, produces the reinforcing effects of tobacco dependence by potentiating dopaminergic and glutamatergic neurotransmission. Non-nicotine alkaloids in tobacco also contribute to dependence by activating the cholinergic system. However, glutamatergic neurotransmission… read more here.
Keywords: glutamate levels; administration; administration cigarette; repeated administration ... See more keywords