LAUSR

Repeated MDA5 Gene Loss in Birds: An Evolutionary Perspective

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1 Published in 2021 at "Viruses"

DOI: 10.3390/v13112131

Abstract: Two key cytosolic receptors belonging to the retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) family sense the viral RNA-derived danger signals: RIG-I and melanoma differentiation-associated protein 5 (MDA5). Their activation establishes an antiviral state by… read more here.

Keywords: loss; mda5 gene; loss birds; gene ... See more keywords