Microstructural and microglial changes after repetitive mild traumatic brain injury in mice
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.23848
Abstract: Traumatic brain injury (TBI) is a major public health issue, with recently increased awareness of the potential long‐term sequelae of repetitive injury. Although TBI is common, objective diagnostic tools with sound neurobiological predictors of outcome… read more here.
Keywords: traumatic brain; brain; repeated mild; mild traumatic ... See more keywords
Repeated mild traumatic brain injury causes persistent changes in histone deacetylase function in hippocampus: Implications in learning and memory deficits in rats
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DOI: 10.1016/j.brainres.2019.01.022
Abstract: Impaired attention and memory represent some of the major long-term consequences of brain injuries. However, little is known about the underlying molecular mechanisms of brain trauma-induced cognitive decline. Histone deacetylases (HDACs) in the hippocampus are… read more here.
Keywords: traumatic brain; learning memory; repeated mild; mild traumatic ... See more keywords
Tau overexpression exacerbates neuropathology after repeated mild head impacts in male mice
Sign Up to like & getrecommendations! Published in 2020 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2019.104683
Abstract: Repeated mild traumatic brain injury (rmTBI) can lead to development of chronic traumatic encephalopathy (CTE), which is characterized by progressive neurodegeneration with presence of white matter damage, gliosis and hyper-phosphorylated tau. While animal models of… read more here.
Keywords: cell; repeated mild; mice; post injury ... See more keywords