Increase of histone acetylation in the GABAergic neurons in the rostral ventromedial medulla associated with mechanical hypersensitivity after repeated restraint stress
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DOI: 10.1016/j.brainresbull.2018.09.004
Abstract: Psychophysical stresses frequently increase sensitivity and response to pain, which is termed stress-induced hyperalgesia (SIH). However, the mechanism remains unknown. The rostral ventromedial medulla (RVM) and locus coeruleus (LC) are core elements of the descending… read more here.
Keywords: acetylation; stress; restraint stress; repeated restraint ... See more keywords
Benefits of tunnel handling persist after repeated restraint, injection and anaesthesia
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DOI: 10.1038/s41598-020-71476-y
Abstract: Millions of mice are used every year for scientific research, representing the majority of scientific procedures conducted on animals. The standard method used to pick up laboratory mice for general husbandry and experimental procedures is… read more here.
Keywords: tail handling; benefits tunnel; mice; repeated restraint ... See more keywords