Articles with "repeated sevoflurane" as a keyword



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Myelination Trajectory and Microglial Dynamics Following Repeated Sevoflurane Exposure in Developing Brain

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Published in 2025 at "Glia"

DOI: 10.1002/glia.70000

Abstract: The myelination is a critical process during brain development. This study aimed to explore the impact of volatile anesthetic sevoflurane on developing myelination and the role of microglial activation in this process. Neonatal C57BL/6J mice… read more here.

Keywords: sevoflurane exposure; repeated sevoflurane; myelination; brain ... See more keywords

Repeated sevoflurane exposures inhibit neurogenesis by inducing the upregulation of glutamate transporter 1 in astrocytes

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Published in 2022 at "European Journal of Neuroscience"

DOI: 10.1111/ejn.15874

Abstract: Sevoflurane is a widely used general anaesthetic in paediatric patients. Although repeated sevoflurane exposure is known to cause neurodevelopmental disorders in children, the mechanism of this neurotoxicity remains largely unknown. Herein, we investigated the role… read more here.

Keywords: repeated sevoflurane; glutamate transporter; sevoflurane exposure; sevoflurane ... See more keywords