Repeat Age Decomposition Informs an Ancient Set of Repeats Associated With Coleoid Cephalopod Divergence
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.793734
Abstract: In comparison with other molluscs and bilaterians, the genomes of coleoid cephalopods (squid, cuttlefish, and octopus) sequenced so far show remarkably different genomic organization that presumably marked the early evolution of this taxon. The main… read more here.
Keywords: repeats associated; repeat; set repeats; divergence ... See more keywords
Structural Characteristics of Simple RNA Repeats Associated with Disease and their Deleterious Protein Interactions
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2017.00097
Abstract: Short Tandem Repeats (STRs) are frequent entities in many transcripts, however, in some cases, pathological events occur when a critical repeat length is reached. This phenomenon is observed in various neurological disorders, such as myotonic… read more here.
Keywords: structural characteristics; associated disease; rna repeats; characteristics simple ... See more keywords
Supramolecular Polymorphism of (G4C2)n Repeats Associated with ALS and FTD
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22094532
Abstract: Guanine-rich DNA sequences self-assemble into highly stable fourfold structures known as DNA-quadruplexes (or G-quadruplexes). G-quadruplexes have furthermore the tendency to associate into one-dimensional supramolecular aggregates termed G-wires. We studied the formation of G-wires in solutions… read more here.
Keywords: g4c2 formed; g4c2; g4c2 repeats; supramolecular polymorphism ... See more keywords