Expanded CUG Repeats Trigger Disease Phenotype and Expression Changes through the RNAi Machinery in C. elegans.
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DOI: 10.1016/j.jmb.2019.03.003
Abstract: Myotonic dystrophy type 1 is an autosomal-dominant inherited disorder caused by the expansion of CTG repeats in the 3' untranslated region of the DMPK gene. The RNAs bearing these expanded repeats have a range of… read more here.
Keywords: repeats trigger; trigger disease; expanded cug; machinery ... See more keywords