A Membrane‐Targeting Aggregation‐Induced Emission Probe for Monitoring Lipid Droplet Dynamics in Ischemia/Reperfusion‐Induced Cardiomyocyte Ferroptosis
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202309907
Abstract: Myocardial ischemia/reperfusion injury (MIRI) is the leading cause of irreversible myocardial damage. A pivotal pathogenic factor is ischemia/reperfusion (I/R)‐induced cardiomyocyte ferroptosis, marked by iron overload and lipid peroxidation. However, the impact of lipid droplet (LD)… read more here.
Keywords: ischemia reperfusion; reperfusion; induced cardiomyocyte; ferroptosis ... See more keywords
Estradiol mitigates ischemia reperfusion-induced acute renal failure through NMDA receptor antagonism in rats
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DOI: 10.1007/s11010-017-3034-9
Abstract: In the present study, we investigated possible involvement of N-methyl-d-aspartate receptors (NMDAR) in estradiol mediated protection against ischemia reperfusion (I/R)-induced acute renal failure (ARF) in rats. Bilateral renal ischemia of 40 min followed by reperfusion for… read more here.
Keywords: estradiol mediated; acute renal; reperfusion; reperfusion induced ... See more keywords
Piperine pretreatment attenuates renal ischemia-reperfusion induced liver injury
Sign Up to like & getrecommendations! Published in 2019 at "Heliyon"
DOI: 10.1016/j.heliyon.2019.e02180
Abstract: Background Remote organ injury is one of the complications which are developed following ischemia-reperfusion induced acute kidney injury (AKI), dramatically increasing its mortality rate. The aim of the present study was to investigate the effect… read more here.
Keywords: reperfusion; piperine pretreatment; reperfusion induced; ischemia reperfusion ... See more keywords
Achyranthes aspera Linn. alleviates cerebral ischemia-reperfusion-induced neurocognitive, biochemical, morphological and histological alterations in Wistar rats.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2018.09.018
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE In the traditional system of Indian medicine, the whole plant and roots of Achyranthes aspera L have been extensively used to treat neurological conditions such as epilepsy and stroke by the various ethnic… read more here.
Keywords: achyranthes aspera; reperfusion; reperfusion induced; ischemia reperfusion ... See more keywords
Cryptotanshinone Attenuates Ischemia/Reperfusion-induced Apoptosis in Myocardium by Upregulating MAPK3.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cardiovascular pharmacology"
DOI: 10.1097/fjc.0000000000000971
Abstract: ABSTRACT Chinese people have used the root of Salvia miltiorrhiza Bunge (called "Danshen" in Chinese) for centuries as an anticancer agent, anti-inflammatory agent, antioxidant, and cardiovascular disease drug. In addition, Danshen is considered to be… read more here.
Keywords: apoptosis; danshen; pharmacology; reperfusion induced ... See more keywords
Effects of chronic inhibition of Testosterone metabolism on cardiac remodeling after ischemia/reperfusion-induced myocardial damage in gonadectomized rats
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DOI: 10.1242/bio.041905
Abstract: ABSTRACT The effects of testosterone on cardiovascular homeostasis are still not well understood. The objective of this work was to evaluate the effects of testosterone in the absence or presence of inhibition of Aromatase (4-hydroxyandrostenedione)… read more here.
Keywords: inhibition; reperfusion induced; ischemia reperfusion; induced myocardial ... See more keywords
miRNA transfection via poly(amidoamine)-based delivery vector prevents hypoxia/reperfusion-induced cardiomyocyte apoptosis.
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DOI: 10.2217/nnm-2019-0363
Abstract: Aim: Myocardial infarction is a tissue injury that leads to apoptosis of cardiomyocytes. This can be prevented by using miRNAs, but its delivery to cardiomyocytes is a major hurdle. We aimed to deliver miRNAs using… read more here.
Keywords: hypoxia reperfusion; apoptosis; delivery; reperfusion induced ... See more keywords
Panax notoginseng Saponins Protect Cerebral Microvascular Endothelial Cells against Oxygen-Glucose Deprivation/Reperfusion-Induced Barrier Dysfunction via Activation of PI3K/Akt/Nrf2 Antioxidant Signaling Pathway
Sign Up to like & getrecommendations! Published in 2018 at "Molecules"
DOI: 10.3390/molecules23112781
Abstract: Oxidative stress plays a critical role in cerebral ischemia/reperfusion (I/R)-induced blood-brain barrier (BBB) disruption. Panax notoginseng saponins (PNS) possess efficient antioxidant activity and have been used in the treatment of cerebral ischemic stroke in China.… read more here.
Keywords: notoginseng saponins; panax notoginseng; cerebral microvascular; reperfusion ... See more keywords