Antigen receptor repertoire profiling from RNA-seq data
Sign Up to like & getrecommendations! Published in 2017 at "Nature Biotechnology"
DOI: 10.1038/nbt.3979
Abstract: Somatic recombination and accumulation of mutations in V-D-J segments result in vast heterogeneity of T-cell receptor (TCR) and immunoglobulin repertoires1,2. High-throughput profiling of immune receptors has become an important tool for studies of adaptive immunity… read more here.
Keywords: profiling rna; repertoire profiling; rna seq; receptor ... See more keywords
Immune repertoire profiling for disease pathobiology
Sign Up to like & getrecommendations! Published in 2022 at "Pathology International"
DOI: 10.1111/pin.13284
Abstract: Lymphocytes consist of highly heterogeneous populations, each expressing a specific cell surface receptor corresponding to a particular antigen. Lymphocytes are both the cause and regulator of various diseases, including autoimmune/allergic diseases, lifestyle diseases, neurodegenerative diseases,… read more here.
Keywords: immune repertoire; repertoire sequencing; pathology; repertoire ... See more keywords