T Cell Receptor Repertoire Sequencing.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0904-0_1
Abstract: The status of T cell receptors (TCRs) repertoire is associated with the occurrence and progress of various diseases and can be used in monitoring the immune responses, predicting the prognosis of disease and other medical… read more here.
Keywords: cell receptor; repertoire sequencing; biology; repertoire ... See more keywords
TCR REPERTOIRE SEQUENCING OF TOTAL T CELLS AND CIRCULATING FOLLICULAR HELPER T CELLS IN KIDNEY TRANSPLANT RECIPIENTS
Sign Up to like & getrecommendations! Published in 2020 at "Transplantation"
DOI: 10.1097/01.tp.0000699360.18476.e0
Abstract: Patricia Almendro Vázquez, Rocío Laguna Goya, Alberto Utrero Rico, Patricia Suárez Férnandez, Cecila González Cuadrado, Marta Chivite Lacaba, Jara Caro Espado , Esther González Montes, Esther Mancebo Sierra, Estela Paz Artal Immunology, Hospital 12 de… read more here.
Keywords: madrid spain; repertoire sequencing; sequencing total; total cells ... See more keywords
Immune repertoire profiling for disease pathobiology
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DOI: 10.1111/pin.13284
Abstract: Lymphocytes consist of highly heterogeneous populations, each expressing a specific cell surface receptor corresponding to a particular antigen. Lymphocytes are both the cause and regulator of various diseases, including autoimmune/allergic diseases, lifestyle diseases, neurodegenerative diseases,… read more here.
Keywords: immune repertoire; repertoire sequencing; pathology; repertoire ... See more keywords
PO-394 Performance of a targeted T cell receptor beta immune repertoire sequencing panel in several FFPE tissue types – a tool for interrogation of the tumour microenvironment
Sign Up to like & getrecommendations! Published in 2018 at "ESMO Open"
DOI: 10.1136/esmoopen-2018-eacr25.906
Abstract: Introduction T cell receptor beta (TCRβ) immune repertoire analysis by next-generation sequencing is a valuable tool for research studies of the tumour microenvironment and potential immune responses to cancer immunotherapy. Here we describe a TCRβ… read more here.
Keywords: immune repertoire; input; tissue; repertoire sequencing ... See more keywords
Simple paired heavy- and light-chain antibody repertoire sequencing using endoplasmic reticulum microsomes
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DOI: 10.1186/s13073-018-0542-5
Abstract: Existing methods for paired antibody heavy- and light-chain repertoire sequencing rely on specialized equipment and are limited by their commercial availability and high costs. Here, we report a novel simple and cost-effective emulsion-based single-cell paired… read more here.
Keywords: repertoire; antibody repertoire; repertoire sequencing; light chain ... See more keywords
Computational Model Reveals Limited Correlation between Germinal Center B-Cell Subclone Abundancy and Affinity: Implications for Repertoire Sequencing
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.00221
Abstract: Immunoglobulin repertoire sequencing has successfully been applied to identify expanded antigen-activated B-cell clones that play a role in the pathogenesis of immune disorders. One challenge is the selection of the Ag-specific B cells from the… read more here.
Keywords: subclone; abundancy affinity; affinity; repertoire sequencing ... See more keywords
Utility of Bulk T-Cell Receptor Repertoire Sequencing Analysis in Understanding Immune Responses to COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12051222
Abstract: Measuring immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 19 (COVID-19), can rely on antibodies, reactive T cells and other factors, with T-cell-mediated responses appearing to have greater… read more here.
Keywords: cell; tcr repertoire; repertoire sequencing; analysis ... See more keywords