Articles with "replacement mutations" as a keyword



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B cell M-CLL clones retain selection against replacement mutations in their immunoglobulin gene framework regions

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Published in 2023 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2023.1115361

Abstract: Introduction Chronic lymphocytic leukemia (CLL) is the most common adult leukemia, accounting for 30–40% of all adult leukemias. The dynamics of B-lymphocyte CLL clones with mutated immunoglobulin heavy chain variable region (IgHV) genes in their… read more here.

Keywords: dominant clones; replacement mutations; selection replacement; cll clones ... See more keywords