Molecular Analyses Support the Safety and Activity of Retroviral Replicating Vector Toca 511 in Patients
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DOI: 10.1158/1078-0432.ccr-18-0619
Abstract: Purpose: Toca 511 is a gammaretroviral replicating vector encoding cytosine deaminase that selectively infects tumor cells and converts the antifungal drug 5-fluorocytosine into the antineoplastic drug 5-fluorouracil, which directly kills tumor cells and stimulates antitumor… read more here.
Keywords: molecular analyses; tumor; replicating vector; toca 511 ... See more keywords