The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.107849
Abstract: SUMMARY Replication-blocking DNA lesions are particularly toxic to proliferating cells because they can lead to chromosome mis-segregation if not repaired prior to mitosis. In this study, we report that ZGRF1 null cells accumulate chromosome aberrations… read more here.
Keywords: dna damage; repair replication; replication blocking; zgrf1 helicase ... See more keywords
The influenza replication blocking inhibitor LASAG does not sensitize human epithelial cells for bacterial infections
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0233052
Abstract: Severe influenza virus (IV) infections still represent a major challenge to public health. To combat IV infections, vaccines and antiviral compounds are available. However, vaccine efficacies vary with very limited to no protection against newly… read more here.
Keywords: epithelial cells; lasag; replication blocking; influenza replication ... See more keywords