Articles with "replication bypass" as a keyword



Replication Bypass of the N-(2-Deoxy-d-erythro-pentofuranosyl)-urea DNA Lesion by Human DNA Polymerase η

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Published in 2024 at "Biochemistry"

DOI: 10.1021/acs.biochem.3c00569

Abstract: Urea lesions in DNA arise from thymine glycol (Tg) or 8-oxo-dG; their genotoxicity is thought to arise in part due to their potential to accommodate the insertion of all four dNTPs during error-prone replication. Replication… read more here.

Keywords: replication bypass; replication; urea lesions; human dna ... See more keywords