E2F-dependent transcription determines replication capacity and S phase length
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DOI: 10.1038/s41467-020-17146-z
Abstract: DNA replication timing is tightly regulated during S-phase. S-phase length is determined by DNA synthesis rate, which depends on the number of active replication forks and their velocity. Here, we show that E2F-dependent transcription, through… read more here.
Keywords: phase; replication capacity; e2f dependent; dependent transcription ... See more keywords
Replication Capacity of Viruses from Acute Infection Drives HIV-1 Disease Progression
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Virology"
DOI: 10.1128/jvi.01806-16
Abstract: ABSTRACT The viral genotype has been shown to play an important role in HIV pathogenesis following transmission. However, the viral phenotypic properties that contribute to disease progression remain unclear. Most studies have been limited to… read more here.
Keywords: progression; replication capacity; disease progression;