Viral DNA Binding Protein SUMOylation Promotes PML Nuclear Body Localization Next to Viral Replication Centers
Sign Up to like & getrecommendations! Published in 2020 at "mBio"
DOI: 10.1128/mbio.00049-20
Abstract: PML nuclear bodies (PML-NBs) are implicated in general antiviral defense based on recruiting host restriction factors; however, it is not understood so far why viruses would establish viral replication centers (RCs) juxtaposed to such “antiviral”… read more here.
Keywords: viral replication; replication centers; replication; pml nuclear ... See more keywords
The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers
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DOI: 10.7554/elife.79676
Abstract: The human SMC5/6 complex is a conserved guardian of genome stability and an emerging component of antiviral responses. These disparate functions likely require distinct mechanisms of SMC5/6 regulation. In yeast, Smc5/6 is regulated by its… read more here.
Keywords: replication centers; slf2; domain; smc5 ... See more keywords