Effects of Epitranscriptomic RNA Modifications on the Catalytic Activity of the SARS‐CoV‐2 Replication Complex **
Sign Up to like & getrecommendations! Published in 2023 at "ChemBioChem"
DOI: 10.1002/cbic.202300095
Abstract: SARS‐CoV‐2 causes individualized symptoms. Many reasons have been given. We propose that an individual's epitranscriptomic system could be responsible as well. The viral RNA genome can be subject to epitranscriptomic modifications, which can be different… read more here.
Keywords: activity sars; replication; m1a; cov replication ... See more keywords
Using Site Specific Fluorescent Probes to Examine Replication Fork Destabilization by Regulatory Proteins of the Bacteriophage T4 DNA Replication Complex
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DOI: 10.1016/j.bpj.2016.11.1705
Abstract: The reconstituted T4 DNA replication complex serves as the simplest model system to examine the ‘core’ replication mechanisms of higher organisms. In this study we used site-specifically introduced fluorescent base analogues to track local conformational… read more here.
Keywords: replication fork; regulatory proteins; dna replication; replication complex ... See more keywords
Hepatitis C Viral Replication Complex
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DOI: 10.3390/v13030520
Abstract: The life cycle of the hepatitis C virus (HCV) can be divided into several stages, including viral entry, protein translation, RNA replication, viral assembly, and release. HCV genomic RNA replication occurs in the replication organelles… read more here.
Keywords: rna replication; hcv genomic; genomic rna; replication complex ... See more keywords
Molecular Insights into the Flavivirus Replication Complex
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DOI: 10.3390/v13060956
Abstract: Flaviviruses are vector-borne RNA viruses, many of which are clinically relevant human viral pathogens, such as dengue, Zika, Japanese encephalitis, West Nile and yellow fever viruses. Millions of people are infected with these viruses around… read more here.
Keywords: insights flavivirus; flavivirus replication; molecular insights; replication complex ... See more keywords