Modeling poliovirus replication dynamics from live time-lapse single-cell imaging data
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DOI: 10.1038/s41598-021-87694-x
Abstract: Viruses experience selective pressure on the timing and order of events during infection to maximize the number of viable offspring they produce. Additionally, they may experience variability in cellular environments encountered, as individual eukaryotic cells… read more here.
Keywords: single cell; imaging data; replication dynamics; replication ... See more keywords
Unusual replication dynamics during Plasmodium falciparum schizogony
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DOI: 10.1186/s12936-025-05610-4
Abstract: Plasmodium falciparum causes the most severe form of malaria in humans, and disease severity is directly linked to parasite proliferation during the erythrocytic cycle. During this cycle, P. falciparum replicates via schizogony. This is an… read more here.
Keywords: replication; dna replication; replication dynamics; schizogony ... See more keywords
Monitoring intracellular replication dynamics unveils high proportion of non-replicating antibiotic-tolerant Staphylococcus aureus inside osteoblasts
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DOI: 10.1371/journal.ppat.1013525
Abstract: Therapeutic failures and relapses are critical challenges in Staphylococcus aureus bone and joint infections. These issues may stem, in part, from the incomplete eradication of S. aureus residing within osteoblasts, the bone-forming cells, despite recommended… read more here.
Keywords: aureus; replication dynamics; high proportion; intracellular replication ... See more keywords