Targeting human cytomegalovirus IE genes by CRISPR/Cas9 nuclease effectively inhibits viral replication and reactivation
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DOI: 10.1007/s00705-020-04687-3
Abstract: Human cytomegalovirus (HCMV) infection causes high morbidity and mortality among immunocompromised patients and can remain in a latent state in host cells. Expression of the immediate-early (IE) genes sustains HCMV replication and reactivation. As a… read more here.
Keywords: reactivation; crispr cas9; human cytomegalovirus; replication reactivation ... See more keywords