Inhibition of the replication of SARS-CoV-2 in human cells by the FDA-approved drug chlorpromazine
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Antimicrobial Agents"
DOI: 10.1016/j.ijantimicag.2020.106274
Abstract: Introduction Urgent action is needed to fight the ongoing COVID-19 pandemic by reducing the number of infected people along with the infection contagiousness and severity. Chlorpromazine (CPZ), the prototype of typical antipsychotics from the phenothiazine… read more here.
Keywords: replication sars; drug; inhibition replication; cpz ... See more keywords
Replication of SARS-CoV-2 in human respiratory epithelium.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of virology"
DOI: 10.1128/jvi.00957-20
Abstract: Currently, there are four seasonal coronaviruses associated with relatively mild respiratory tract disease in humans. However, there are also a plethora of animal coronaviruses, which have the potential to cross the species border. This regularly… read more here.
Keywords: replication sars; biology; epithelium; virus ... See more keywords