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Next-Generation Sequencing-Based Analysis of the Roles of DNA Polymerases ν and θ in the Replicative Bypass of 8-Oxo-7,8-dihydroguanine in Human Cells.

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Published in 2022 at "ACS chemical biology"

DOI: 10.1021/acschembio.2c00415

Abstract: DNA polymerase (Pol) ν and Pol θ are two specialized A-family DNA polymerases that function in the translesion synthesis of certain DNA lesions. However, the biological functions of human Pols ν and θ in cellular… read more here.

Keywords: dna; human cells; dna polymerases; replicative bypass ... See more keywords